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The HPLC procedure can use two independent and reliable means\u2014optical density at 405 nm and radioactivity to determine the adult Hb\/HbF + Fac ratio. The diagnosis is obtained in 15 mm by cation exchange HPLC.<\/jats:p>","DOI":"10.1002\/pd.1970090104","type":"journal-article","created":{"date-parts":[[2007,3,4]],"date-time":"2007-03-04T01:58:42Z","timestamp":1172973522000},"page":"19-26","source":"Crossref","is-referenced-by-count":5,"title":["Prenatal diagnosis of haemoglobinopathies by ion exchange hplc of haemoglobins"],"prefix":"10.1002","volume":"9","author":[{"given":"P.","family":"Rouyer\u2010Fessard","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Plassa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Blouquit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Vidaud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Varnavides","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. 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