{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T11:46:27Z","timestamp":1765885587132},"reference-count":41,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2005,11,21]],"date-time":"2005-11-21T00:00:00Z","timestamp":1132531200000},"content-version":"vor","delay-in-days":6048,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[1989,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Twenty\u2010two cases of cystic hygromas were diagnosed prenatally at Eastern Virginia Medical School and followed through the neonatal period. Our series was combined with 131 cases which have been described in the literature. Karyotypes were obtained in 110 fetuses and 80 (72\u00b77 per cent) were abnormal. Fifty\u2010one were not terminated: 30 with abnormal and 21 with normal karyotypes. There were no neonatal survivors in the group with abnormal karyotypes. There were five survivors in the 21 with normal karyotypes but only 2\/21 without severe medical complications. Combining our series with those previously reported in the literature would suggest only a 2\u20133 per cent rate of intact survivors when fetal cystic hygromas are diagnosed <jats:italic>in utero<\/jats:italic>. This information should be helpful when counselling patients whose pregnancies carry this diagnosis.<\/jats:p>","DOI":"10.1002\/pd.1970090504","type":"journal-article","created":{"date-parts":[[2007,3,4]],"date-time":"2007-03-04T02:44:41Z","timestamp":1172976281000},"page":"321-327","source":"Crossref","is-referenced-by-count":61,"title":["Congenital cystic hygroma of the neck diagnosed prenatally: Outcome with normal and abnormal karyotype"],"prefix":"10.1002","volume":"9","author":[{"given":"Jacques S.","family":"Abramowicz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven L.","family":"Warsof","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Debra Lochner","family":"Doyle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deborah","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donald L.","family":"Levy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,21]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.1870070507"},{"key":"e_1_2_1_3_1","first-page":"618","article-title":"When ultrasound shows fetal abnormality","volume":"1","author":"Anonymous","year":"1985","journal-title":"Lancet"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1093\/ajcp\/76.3.342","article-title":"Hygroma cervices in a 46\u2010XY male stillborn baby","volume":"76","author":"Berant M.","year":"1981","journal-title":"Am. 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