{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:20:59Z","timestamp":1760188859030},"reference-count":17,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2005,11,21]],"date-time":"2005-11-21T00:00:00Z","timestamp":1132531200000},"content-version":"vor","delay-in-days":5652,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[1990,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Between May 1987 and November 1988, 505 early amniocentesis within the 15th week of gestation were performed at the First Department of Obstetrics and Gynaecology,\u2018L. Mangiagalli\u2019 of the University of Milan and at the Department of Obstetrics and Gynaecology of \u2018Gaslini\u2019 hospital in Genoa. A total number often abnormal fetal karyotypes were diagnosed. In addition, one case of pseudomosaicism (not confirmed on fetal blood) and one case of osteogenesis imperfecta type II (observed at ultrasound examination) were also detected. Eleven pregnancies were therefore terminated because of an abnormal fetus. Out of 494 pregnancies (excluding terminated pregnancies) there were 16 fetal losses within the 28th week; ten of these occurred in the 2 weeks following the procedure. There were 475 live\u2010births, of which 447 were term deliveries and the other 28 deliveries occurred before the 37th week of gestation.<\/jats:p>","DOI":"10.1002\/pd.1970100603","type":"journal-article","created":{"date-parts":[[2007,3,4]],"date-time":"2007-03-04T04:13:23Z","timestamp":1172981603000},"page":"359-364","source":"Crossref","is-referenced-by-count":44,"title":["Genetic amniocentesis: 505 cases performed before the sixteenth week of gestation"],"prefix":"10.1002","volume":"10","author":[{"given":"L.","family":"Stripparo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Buscaglia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Longatti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Ghisonl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Dambrosio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Guerneri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Rosella","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Lituania","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Cordone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"De Biasio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U.","family":"Passamonti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Gimelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Cuoco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,21]]},"reference":[{"key":"e_1_2_1_2_1","unstructured":"Ashmead G. G. Dunn L. K. Godmilow L. Librizzi R. J. Weiner S.(1987).Early genetic amniocentesis: a prospective study of 219 patients International Symposium First Trimester Diagnosis and Therapy Chicago Abstract 16."},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.1870100102"},{"key":"e_1_2_1_4_1","unstructured":"Cordone M. Lituania M. Passamonti U. Cuoco C. Pezzolo A.(1987).Feto\u2010placental discrepancies: possible role of first trimester amniocentesis International Symposium First Trimester Genetic Diagnosis and Therapy Chicago Abstract 7."},{"key":"e_1_2_1_5_1","unstructured":"Cuoco C. Gimelli G. Porta S. Pezzolo A. Cordone M. Passamonti U.(1988).First trimester amniocentesis: an alternative to CVS 4th International Conference on Chorionic Villus Sampling and Early Prenatal Diagnosis Athens Abstract 79."},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(85)91997-X"},{"key":"e_1_2_1_7_1","first-page":"A275","article-title":"Genetic amniocentesis between 12 and 14 weeks gestation","volume":"41","author":"Godmilow L.","year":"1987","journal-title":"Am. Hum. Genet."},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(87)90026-3"},{"key":"e_1_2_1_9_1","article-title":"Amniocentesis before 15 weeks instead of CVS for earlier prenatal diagnosis","volume":"37","author":"Henry G.","year":"1985","journal-title":"Am. J. Hum. Genet."},{"key":"e_1_2_1_10_1","unstructured":"Lituania M. Cordone M. S. De Biasio P. Passamonti U. Gimelli G. Cuoco C.(1988).Early genetic amniocentesis: preliminary results on 125 procedures from 11th to the 15th week 4th International Conference on Chorionic Villus Sampling and Early Prenatal Diagnosis Athens Abstract 27."},{"key":"e_1_2_1_11_1","first-page":"A222","article-title":"Prospective evaluation of early amniocentesis for prenatal diagnosis","volume":"37","author":"Luthard F. W.","year":"1985","journal-title":"Am. J. Hum. Genet."},{"key":"e_1_2_1_12_1","first-page":"A281","article-title":"Success, safety and accuracy of early amniocentesis","volume":"41","author":"Miller W. A.","year":"1987","journal-title":"Am. J. Hum. Genet."},{"key":"e_1_2_1_13_1","volume-title":"Embryology of Domestic Animals","author":"Noden D. M.","year":"1985"},{"key":"e_1_2_1_14_1","first-page":"973","article-title":"The effect of ultrasonography on mid trimester amniocentesis complication","volume":"147","author":"Nolan G.","year":"1983","journal-title":"Am. J. Obstet. 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