{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T17:37:22Z","timestamp":1760204242481},"reference-count":9,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2005,11,21]],"date-time":"2005-11-21T00:00:00Z","timestamp":1132531200000},"content-version":"vor","delay-in-days":5622,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[1990,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Five hundred cordocenteses were performed between 12 and 21 weeks. The indications were thalassaemia (386), rapid karyotyping (97), feto\u2010maternal allo\u2010immunization (10), rubella (6), and toxoplasmosis (1). One hundred and ten pregnancies underwent termination on the basis of the result, while 20 of the 370 pregnancies intended to continue were lost to follow\u2010up. Amongst these were 16 fetal losses (4\u00b73 per cent) and 22 premature deliveries (5\u00b79 per cent); no other complications were reported. Four adverse prognostic factors were identified: (a) cord bleeding; (b) fetal bradycardia; (c) prolonged procedure time; and (d) anterior insertion of the placenta. There was no\u2018obvious\u2019 difference in fetal loss rate with advancing gestation until 19\u201321 weeks, when the risk of fetal loss decreased to 2\u00b75 per cent.<\/jats:p>","DOI":"10.1002\/pd.1970100703","type":"journal-article","created":{"date-parts":[[2007,3,4]],"date-time":"2007-03-04T04:08:15Z","timestamp":1172981295000},"page":"425-428","source":"Crossref","is-referenced-by-count":72,"title":["The risks of early cordocentesis (12\u201321 weeks): Analysis of 500 procedures"],"prefix":"10.1002","volume":"10","author":[{"given":"F.","family":"Orlandi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Damiani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Jakil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Lauricella","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Bertolino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Maggio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,21]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(76)90748-1"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1970030402"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1980.tb05914.x"},{"key":"e_1_2_1_5_1","first-page":"105","article-title":"Practical approaches to the control of thalassaemia","volume":"52","author":"Modell C. B.","year":"1976","journal-title":"Postgrad. Med. J."},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(87)80344-7"},{"key":"e_1_2_1_7_1","first-page":"329","article-title":"Clinical results and fetal biochemical data on 140 early second trimester diagnostic cordocentesis","volume":"18","author":"Orlandi F.","year":"1987","journal-title":"Acta Eur. Fert."},{"key":"e_1_2_1_8_1","unstructured":"Orlandi F. Damiani G. Jakil C. Lauricella S. Pignatone C. Maggio A.(1988a). 218 cordocentesi diagnostiche effettuate nel secondo trimestre precoce. Casistica e valori emogasanalitici fetali Ultrasonica III 19\u201324."},{"key":"e_1_2_1_9_1","first-page":"23","article-title":"First trimester fetal blood sampling","volume":"19","author":"Orlandi F.","year":"1988","journal-title":"Acta Eur. Fert."},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1970030304"}],"container-title":["Prenatal Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.1970100703","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pd.1970100703","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T22:58:23Z","timestamp":1698015503000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/pd.1970100703"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,7]]},"references-count":9,"journal-issue":{"issue":"7","published-print":{"date-parts":[[1990,7]]}},"alternative-id":["10.1002\/pd.1970100703"],"URL":"https:\/\/doi.org\/10.1002\/pd.1970100703","archive":["Portico"],"relation":{},"ISSN":["0197-3851","1097-0223"],"issn-type":[{"value":"0197-3851","type":"print"},{"value":"1097-0223","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,7]]}}}