{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T14:50:27Z","timestamp":1791298227746,"version":"4.1.0"},"reference-count":12,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2005,11,21]],"date-time":"2005-11-21T00:00:00Z","timestamp":1132531200000},"content-version":"vor","delay-in-days":5530,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[1990,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report an infant with a craniopharyngioma which was detected <jats:italic>in utero<\/jats:italic>. Maternal uterine ultrasonography, done at 27 weeks because of polyhydramnios, revealed a 4 cm midline mass near the base of the fetal skull. At 31 weeks, magnetic resonance imaging of the maternal abdomen confirmed the presence of a mass in the region of the third ventricle and revealed hydrocephalus. Two days post\u2010partum a computed tomography (CT)\u2010guided needle biopsy of the mass was performed and recovered tissue which was histologically consistent with a craniopharyngioma. The infant' s postnatal period was complicated by seizures, which were treated with phenobarbital, and by progressive hydrocephalus, necessitating placement of a ventriculo\u2010peritoneal shunt. He also received therapy for central hypothyroidism and diabetes insipidus. The infant' s parents refused permission for attempted resection of the tumour and he died at 8 weeks of age.<\/jats:p><jats:p>This represents the second reported case of an antenatally detected craniopharyngioma. Four other cases of different intracranial tumours have been detected <jats:italic>in utero<\/jats:italic> using ultrasound, with no reported survivors past 3 days of age. There is a uniformly poor prognosis of such infants, but earlier diagnosis and intervention may change this result.<\/jats:p>","DOI":"10.1002\/pd.1970101002","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T23:07:25Z","timestamp":1172963245000},"page":"623-629","source":"Crossref","is-referenced-by-count":31,"title":["Prenatal diagnosis of a craniopharyngioma using ultrasonography and magnetic resonance imaging"],"prefix":"10.1002","volume":"10","author":[{"given":"Wendy","family":"Bailey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary R.","family":"Freidenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hector E.","family":"James","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John R.","family":"Hesselink","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth Lee","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,11,21]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.247.8.1173"},{"key":"e_1_2_1_3_1","first-page":"111","volume-title":"Clinical Neuroimaging","author":"Fishbein D. S.","year":"1988"},{"key":"e_1_2_1_4_1","first-page":"81","article-title":"Neonatal craniopharyngioma","volume":"88","author":"Freeman T. B.","year":"1988","journal-title":"N. Y. State J. Med."},{"key":"e_1_2_1_5_1","first-page":"247","article-title":"Prenatal ultrasound diagnosis of intracranial teratoma","volume":"8","author":"Hoff N. R.","year":"1980","journal-title":"J. C. U."},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1977.47.2.0218"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1515\/jpme.1982.10.6.257"},{"key":"e_1_2_1_8_1","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1007\/BF00271388","article-title":"Brain tumors in infants: a study of 76 patients operated upon","volume":"4","author":"Lapras C.","year":"1988","journal-title":"Child's Nerv. 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U."},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00690807"}],"container-title":["Prenatal Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.1970101002","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pd.1970101002","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T11:30:07Z","timestamp":1697974207000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/pd.1970101002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,10]]},"references-count":12,"journal-issue":{"issue":"10","published-print":{"date-parts":[[1990,10]]}},"alternative-id":["10.1002\/pd.1970101002"],"URL":"https:\/\/doi.org\/10.1002\/pd.1970101002","archive":["Portico"],"relation":{},"ISSN":["0197-3851","1097-0223"],"issn-type":[{"value":"0197-3851","type":"print"},{"value":"1097-0223","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,10]]}}}