{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T19:21:26Z","timestamp":1700248886482},"reference-count":15,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2005,11,21]],"date-time":"2005-11-21T00:00:00Z","timestamp":1132531200000},"content-version":"vor","delay-in-days":5134,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[1991,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The study of the fetal platelet count and size can, according to the literature, be used for the prenatal diagnosis of the Wiskott\u2010Aldrich syndrome (WAS). So far, no affected fetuses have been identified by this method. All pregnancies in which this method had been applied to resulted, as correctly predicted, in the birth of normal children. Here we report on a familial case of WAS where the haematological parameters failed to reveal the affected second child. Hence we assume that the platelet count and size of platelets remain normal in fetuses with WAS to the gestational age of 22 weeks and cannot be used for prenatal diagnosis.<\/jats:p>","DOI":"10.1002\/pd.1970111103","type":"journal-article","created":{"date-parts":[[2007,3,4]],"date-time":"2007-03-04T04:15:05Z","timestamp":1172981705000},"page":"819-825","source":"Crossref","is-referenced-by-count":4,"title":["False\u2010negative prenatal exclusion of Wiskott\u2010Aldrich syndrome by measurement of fetal platelet count and size"],"prefix":"10.1002","volume":"11","author":[{"given":"Peter","family":"Lorenz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rainer","family":"Bollmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georg Klaus","family":"Hinkel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"M\u00e4chler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriele","family":"Siegert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gudrun","family":"Stamminger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00f6rg","family":"Wendisch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabine","family":"Ziemer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,21]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1542\/peds.13.2.133","article-title":"Pedigree demonstrating a sex\u2010linked recessive condition characterized by drained ears, eczematoid dermatitis and bloody diarrhea","volume":"13","author":"Aldrich A.","year":"1954","journal-title":"Pediatrics"},{"key":"e_1_2_1_3_1","first-page":"906","article-title":"Germ\u2010line mosaicism simulates genetic heterogeneity in Wiskott\u2010Aldrich syndrome","volume":"46","author":"Arveiler B.","year":"1990","journal-title":"Am. J. Hum. Genet."},{"key":"e_1_2_1_4_1","first-page":"85","article-title":"Das Wiskott\u2010Aldrich Syndrom","volume":"41","author":"Belohradsky B. H.","year":"1978","journal-title":"Ergeb. Inn. Med. 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Kinderheilkd."}],"container-title":["Prenatal Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.1970111103","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pd.1970111103","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T05:12:31Z","timestamp":1698037951000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/pd.1970111103"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,11]]},"references-count":15,"journal-issue":{"issue":"11","published-print":{"date-parts":[[1991,11]]}},"alternative-id":["10.1002\/pd.1970111103"],"URL":"https:\/\/doi.org\/10.1002\/pd.1970111103","archive":["Portico"],"relation":{},"ISSN":["0197-3851","1097-0223"],"issn-type":[{"value":"0197-3851","type":"print"},{"value":"1097-0223","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,11]]}}}