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This suggests that in oligohydramnios the origin of excess AFP in the maternal compartment is amniotic fluid. It is proposed that oligohydramnios and the associated raised maternal serum AFP levels are caused by damage of the fetal membranes prior to 16 weeks of gestation resulting in leakage of amniotic fluid to the decidual tissue and resorption in the maternal circulation.<\/jats:p>","DOI":"10.1002\/pd.1970120106","type":"journal-article","created":{"date-parts":[[2007,3,4]],"date-time":"2007-03-04T05:52:27Z","timestamp":1172987547000},"page":"39-45","source":"Crossref","is-referenced-by-count":7,"title":["Origin of raised maternal serum alpha\u2010fetoprotein levels in second\u2010trimester oligohydramnios"],"prefix":"10.1002","volume":"12","author":[{"given":"F. J.","family":"Los","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. 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