{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T16:22:11Z","timestamp":1759422131925},"reference-count":13,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2005,11,21]],"date-time":"2005-11-21T00:00:00Z","timestamp":1132531200000},"content-version":"vor","delay-in-days":4495,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[1993,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We studied the opinions and experiences concerning maternal serum screening of two groups of women: (A) women who were not eligible for prenatal diagnosis; and (B) women for whom prenatal diagnosis was available because of advanced maternal age, and who either underwent chorionic villus sampling or amniocentesis. Many of the women were in favour of the availability of serum screening and would apply for this test in a future pregnancy. This applied also to many respondents who had previously undergone prenatal diagnosis. Most of these women, however, did not intend to decline diagnostic amniocentesis if the screening results did not indicate an increased risk. The majority of the group of respondents of 36 years and over did not consider it acceptable if age indication was dropped altogether.<\/jats:p><jats:p>A system based on serum screening will have other implications than a policy based on age indication, since specific individual risk assessment is perceived as being of more significance than a risk statistically derived from age alone. Serum screening is often seen as a means of reassurance and many women are not aware of the possible drawbacks. As technology becomes increasingly complicated, counselling has to be adjusted correspondingly. Further research is needed to establish whether and how distress can be minimized and well\u2010considered individual choice can be achieved.<\/jats:p>","DOI":"10.1002\/pd.1970130808","type":"journal-article","created":{"date-parts":[[2007,3,4]],"date-time":"2007-03-04T06:47:34Z","timestamp":1172990854000},"page":"741-747","source":"Crossref","is-referenced-by-count":30,"title":["Women's opinions on the offer and use of maternal serum screening"],"prefix":"10.1002","volume":"13","author":[{"given":"E. E. C.","family":"Roelofsen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. I.","family":"Kamerbeek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tj.","family":"Tymstra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. R.","family":"Beekhuis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Mantingh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,21]]},"reference":[{"key":"e_1_2_1_2_1","unstructured":"Annual Report Committee of the Working Party on Prenatal Diagnosis(1989).Annual Report 1989 Utrecht:Working Party on Prenatal Diagnosis of the Dutch Society of Obstetrics and Gynaecology and the Dutch Society of Clinical Genetics 10\u201311."},{"key":"e_1_2_1_3_1","unstructured":"Beekhuis J. R. van Lith J. M. M. de Wolf B. T. H. M. Mantingh A. Breed A. S. P. M.(1992).Maternal serum screening for fetal neural tube defects and Down's syndrome; first Dutch experience Ned. Tijdschr. Geneeskd. in press."},{"key":"e_1_2_1_4_1","volume-title":"An Evaluation of Cytogenetic Diagnosis by Chorionic Villus Sampling: Reliability and Implications","author":"Breed A. S. P. M.","year":"1992"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.297.6653.876"},{"key":"e_1_2_1_6_1","volume-title":"The Sexual Politics of Reproduction","author":"Farrant W.","year":"1985"},{"key":"e_1_2_1_7_1","volume-title":"Calming or Harming? A Critical Review of Psychological Effects of Fetal Diagnosis on Pregnant Women","author":"Green J. M.","year":"1990"},{"key":"e_1_2_1_8_1","first-page":"1096","article-title":"Preventief onderzoek van zwangeren op defecten van de neurale buis van de foetus door bepaling van het gehalte aan a\u2010foetoprote\u00efne in het serum","volume":"124","author":"Los F. J.","year":"1980","journal-title":"Ned. Tijdschr. Geneeskd."},{"key":"e_1_2_1_9_1","volume-title":"Screening in Prenatal Diagnosis","author":"Mantingh A.","year":"1991"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1970120309"},{"key":"e_1_2_1_11_1","volume-title":"Beleidsstandpunt bevolkingsonderzoek neuraalbuisdefectenl Down syndroom, WVC Kenmerk PEP\/GZ 912459","author":"Simons H. J.","year":"1991"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0266462300006437"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1970111203"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.297.6653.883"}],"container-title":["Prenatal Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.1970130808","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pd.1970130808","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,24]],"date-time":"2023-10-24T22:03:25Z","timestamp":1698185005000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/pd.1970130808"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,8]]},"references-count":13,"journal-issue":{"issue":"8","published-print":{"date-parts":[[1993,8]]}},"alternative-id":["10.1002\/pd.1970130808"],"URL":"https:\/\/doi.org\/10.1002\/pd.1970130808","archive":["Portico"],"relation":{},"ISSN":["0197-3851","1097-0223"],"issn-type":[{"value":"0197-3851","type":"print"},{"value":"1097-0223","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,8]]}}}