{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T15:03:02Z","timestamp":1770822182587,"version":"3.50.1"},"reference-count":4,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2005,11,22]],"date-time":"2005-11-22T00:00:00Z","timestamp":1132617600000},"content-version":"vor","delay-in-days":4223,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[1994,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In the North\u2010Western Region we offer a service to examine fetuses aborted after the diagnosis of fetal abnormalities. Many obstetricians use this service. We examined 343 mid\u2010trimester fetuses over the last 5 years: 215 following an abnormal scan and 128 abnormal amniotic fluid or villus findings. When necessary, investigations were performed. A post\u2010mortem examination was always required. As a result of fetal investigation, the scan diagnosis was modified or refined in 91 cases (42\u00b73 per cent). In three of these cases, no fetal abnormality was found. For the fetuses diagnosed as abnormal by amniocentesis or chorionic villus biopsy, in one (0\u00b78 per cent) the pre\u2010termination diagnosis was not confirmed. The results were similar to those of our previous 5\u2010year study except (a) diagnosis of neural tube defects was rarely based on amniocentesis in the present study (2\/62, 3\u00b72 per cent) compared with the previous one (32\/103, 31 per cent), and (b) renal abnormalities were more often diagnosed in the pre\u2010termination scan in the present study. We conclude that the examination of aborted mid\u2010trimester fetuses by dysmorphologists continues to improve diagnosis, allowing more accurate genetic counselling for the families.<\/jats:p>","DOI":"10.1002\/pd.1970140507","type":"journal-article","created":{"date-parts":[[2007,3,4]],"date-time":"2007-03-04T09:43:16Z","timestamp":1173001396000},"page":"381-385","source":"Crossref","is-referenced-by-count":19,"title":["Examination of fetuses after induced abortion for fetal abnormality\u2014a follow\u2010up study"],"prefix":"10.1002","volume":"14","author":[{"given":"A.","family":"Medeira","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Norman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Haslam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Clayton\u2010Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Donnai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,22]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.300.6720.295"},{"key":"e_1_2_1_3_1","first-page":"719","volume-title":"Prenatal Diagnosis and Screening","author":"Keeling J. W.","year":"1992"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1970080205"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/15513818909022327"}],"container-title":["Prenatal Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.1970140507","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pd.1970140507","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,24]],"date-time":"2023-10-24T00:30:43Z","timestamp":1698107443000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/pd.1970140507"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,5]]},"references-count":4,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1994,5]]}},"alternative-id":["10.1002\/pd.1970140507"],"URL":"https:\/\/doi.org\/10.1002\/pd.1970140507","archive":["Portico"],"relation":{},"ISSN":["0197-3851","1097-0223"],"issn-type":[{"value":"0197-3851","type":"print"},{"value":"1097-0223","type":"electronic"}],"subject":[],"published":{"date-parts":[[1994,5]]}}}