{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T06:07:07Z","timestamp":1761718027448},"reference-count":12,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2005,11,22]],"date-time":"2005-11-22T00:00:00Z","timestamp":1132617600000},"content-version":"vor","delay-in-days":4100,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[1994,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>2267 singleton fetuses who had one ultrasound examination between 15 and 21 weeks' gestation were prospectively evaluated for echogenic small bowel. Thirty\u2010two cases of echogenic small bowel were detected\u2014a prevalence of 1\u00b74 per cent. Echogenic fetal small bowel was divided into two grades: grade 1, where the small bowel was more echogenic than the liver; and grade 2, where the small bowel had the echogenicity of bone. In contrast to 19\/23 fetuses with grade 1 small bowel echogenicity, only 2\/9 fetuses with grade 2 echogenic bowel had a normal pregnancy outcome (Fisher's exact test; <jats:italic>P<\/jats:italic>\u2a7d0\u00b701). Complications associated with second\u2010trimester echogenic small bowel included <jats:italic>in utero<\/jats:italic> cytomegalovirus infection, second\u2010trimester growth restriction, intrauterine fetal demise, and chromosomal abnormalities. Second\u2010trimester fetal echogenic small bowel is associated with an increased risk of an adverse outcome. The prevalence of perinatal and neonatal complications is significantly greater when small bowel echogenicity approaches that of bone.<\/jats:p>","DOI":"10.1002\/pd.1970140913","type":"journal-article","created":{"date-parts":[[2007,3,4]],"date-time":"2007-03-04T10:05:33Z","timestamp":1173002733000},"page":"845-850","source":"Crossref","is-referenced-by-count":55,"title":["Second\u2010trimester echogenic small bowel: An increased risk for adverse perinatal outcome"],"prefix":"10.1002","volume":"14","author":[{"given":"Lyndon M.","family":"Hill","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanne","family":"Fries","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie","family":"Hecker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia","family":"Grzybek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,22]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1970080508"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1970120802"},{"key":"e_1_2_1_4_1","first-page":"778","article-title":"Sonographically detected hyperechoic fetal bowel: significance and implications for pregnancy management","volume":"80","author":"Dicke J. M.","year":"1992","journal-title":"Obstet. Gynecol."},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.1986.5.9.489"},{"key":"e_1_2_1_6_1","first-page":"535","article-title":"Fetal abdominal echogenic mass: an early sign of intrauterine cytomegalovirus infection","volume":"80","author":"Forouzan I.","year":"1992","journal-title":"Obstet. Gynecol."},{"key":"e_1_2_1_7_1","first-page":"S72","article-title":"Increased abdominal echogenicity in utero: a marker of intestinal obstruction? Abstract 3063. AIUM Convention","volume":"12","author":"Gollin Y. G.","year":"1993","journal-title":"J. Ultrasound Med."},{"key":"e_1_2_1_8_1","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1016\/S0016-5085(76)80277-6","article-title":"Development of the human gastrointestinal tract. A review","volume":"70","author":"Grand R. J.","year":"1976","journal-title":"Gastroenterology"},{"key":"e_1_2_1_9_1","first-page":"370","article-title":"Prenatal sonographic findings of Down syndrome: review of 94 cases","volume":"76","author":"Nyberg D. A.","year":"1990","journal-title":"Obstet. Gynecol."},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.188.2.8327709"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(12)90602-X"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(12)80007-X"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(12)90876-5"}],"container-title":["Prenatal Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.1970140913","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pd.1970140913","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,25]],"date-time":"2023-10-25T07:32:38Z","timestamp":1698219158000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/pd.1970140913"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,9]]},"references-count":12,"journal-issue":{"issue":"9","published-print":{"date-parts":[[1994,9]]}},"alternative-id":["10.1002\/pd.1970140913"],"URL":"https:\/\/doi.org\/10.1002\/pd.1970140913","archive":["Portico"],"relation":{},"ISSN":["0197-3851","1097-0223"],"issn-type":[{"value":"0197-3851","type":"print"},{"value":"1097-0223","type":"electronic"}],"subject":[],"published":{"date-parts":[[1994,9]]}}}