{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T16:24:01Z","timestamp":1762100641334},"reference-count":17,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2005,11,22]],"date-time":"2005-11-22T00:00:00Z","timestamp":1132617600000},"content-version":"vor","delay-in-days":4070,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[1994,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We studied 693 consecutive early amniocenteses (prior to 15 weeks) and found a spontaneous abortion rate to 28 weeks' gestation of 1\u00b75 per cent. A control group of women having standard amniocentesis (15\u201320 weeks) experienced a 0\u00b76 per cent fetal loss in the same period. There were no other apparent differences between the two groups. Early amniocentesis results are generally available 4\u20136 weeks before standard amniocentesis and 1\u20133 weeks after chorionic villus sampling (CVS). Alpha\u2010fetoprotein (AFP) can be accurately assayed in 11\u2010 to 15\u2010week amniotic fluid samples but additional studies are necessary to determine the accuracy of neural tube defect (NTD) detection. Including the present study, over 5800 early amniocenteses have been reported and the results suggest that this is a relatively safe prenatal diagnostic test and an alternative to CVS and later amniocentesis.<\/jats:p>","DOI":"10.1002\/pd.1970141004","type":"journal-article","created":{"date-parts":[[2007,3,4]],"date-time":"2007-03-04T06:51:35Z","timestamp":1172991095000},"page":"913-919","source":"Crossref","is-referenced-by-count":25,"title":["Risk assessment of amniocentesis between 11 and 15 weeks: Comparison to later amniocentesis controls"],"prefix":"10.1002","volume":"14","author":[{"given":"Barbara F.","family":"Crandall","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peggy","family":"Kulch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khalil","family":"Tabsh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,22]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"726","article-title":"Limb anomalies associated with chorionic villus sampling","volume":"79","author":"Burton B. 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