{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T15:59:36Z","timestamp":1775231976025,"version":"3.50.1"},"reference-count":28,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2005,12,14]],"date-time":"2005-12-14T00:00:00Z","timestamp":1134518400000},"content-version":"vor","delay-in-days":3788,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[1995,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report a case of paternal uniparental disomy for chromosome 11 that presented as severe intrauterine growth retardation. Autopsy following intrauterine death also revealed aberrant intestinal rotation and hypospadias. Chromosome analysis of direct preparations from placental biopsy showed an abnormal 47,XY,+11 karyotype. Analysis of long\u2010term cultures from the placenta revealed 46,XY\/47,XY,+11 mosaicism. Fluorescence <jats:italic>in situ<\/jats:italic> hybridization (FISH) studies on interphase nuclei confirmed trisomy 11 in multiple placental sites but detected only disomic cells in fetal skin. Investigation using microsatellite polymorphisms demonstrated paternal isodisomy at loci D11S909, D11S956, and D11S488, and paternal heterodisomy at locus D11S928.<\/jats:p>","DOI":"10.1002\/pd.1970150816","type":"journal-article","created":{"date-parts":[[2007,3,4]],"date-time":"2007-03-04T11:11:58Z","timestamp":1173006718000},"page":"773-777","source":"Crossref","is-referenced-by-count":22,"title":["A case of paternal uniparental disomy for chromosome 11"],"prefix":"10.1002","volume":"15","author":[{"given":"A.","family":"Webb","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Beard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Wright","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Robson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Wolstenholme","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Goodship","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,14]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1970140506"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/351153a0"},{"key":"e_1_2_1_4_1","first-page":"1","volume-title":"Advances in Human Genetics 14","author":"Bou\u00e9 A.","year":"1984"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1970100206"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/2.1.89"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1970080610"},{"key":"e_1_2_1_8_1","first-page":"701","article-title":"Trisomy 15 with loss of the paternal 15 as a cause of Prader\u2010Willi syndrome due to maternal disomy","volume":"51","author":"Cassidy S. B.","year":"1992","journal-title":"Am. J. Hum. Genet."},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(92)92981-K"},{"key":"e_1_2_1_10_1","first-page":"656","article-title":"Cytogenetic analysis of 750 spontaneous abortions with the direct\u2010preparation method of chorionic villi and its implications for studying genetic causes of pregnancy wastage","volume":"47","author":"Eiben B.","year":"1990","journal-title":"Am. J. Hum. Genet."},{"key":"e_1_2_1_11_1","first-page":"208","article-title":"Chorionic villus sampling: experience with an initial 940 cases","volume":"71","author":"Green J. E.","year":"1988","journal-title":"Obstet. Gynecol."},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)91937-P"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00218904"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/351665a0"},{"key":"e_1_2_1_15_1","first-page":"97","article-title":"Trisomy 11 p 15 and Beckwith\u2010Wiedemann syndrome","volume":"28","author":"Journel H.","year":"1985","journal-title":"Ann. Genet."},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1970111002"},{"key":"e_1_2_1_17_1","first-page":"8","article-title":"Uniparental disomy for chromosome 16 in humans","volume":"52","author":"Kalousek D. K.","year":"1993","journal-title":"Am. J. Hum. Genet."},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1970120503"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.295.6595.407"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1970110815"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320240107"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng0593-94"},{"key":"e_1_2_1_23_1","first-page":"1348","article-title":"Uniparental disomy 15 resulting from \u2018correction\u2019 of an initial trisomy 15","volume":"50","author":"Purvis\u2010Smith S. G.","year":"1992","journal-title":"Am. J. Hum. Genet."},{"key":"e_1_2_1_24_1","first-page":"149","article-title":"The U. K. Human Genome Mapping Project online computing service","volume":"8","author":"Rysavy F. R.","year":"1992","journal-title":"Comput. Applications Biosci."},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1970090807"},{"key":"e_1_2_1_26_1","volume-title":"Chromosome Anomalies and Prenatal Development: an Atlas","author":"Warburton D.","year":"1991"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1093-143"},{"key":"e_1_2_1_28_1","first-page":"1262","article-title":"A large, dominant pedigree of atrioventricular septal defect (AVSD): exclusion from the Down syndrome critical region on chromosome 21","volume":"53","author":"Wilson L.","year":"1993","journal-title":"Am. J. Hum. Genet."},{"key":"e_1_2_1_29_1","doi-asserted-by":"crossref","unstructured":"Wolstenholme J.(1995). An audit of trisomy 16 in man Prenat. Diagn. in press.","DOI":"10.1002\/pd.1970150202"}],"container-title":["Prenatal Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.1970150816","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pd.1970150816","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,27]],"date-time":"2023-10-27T04:21:22Z","timestamp":1698380482000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/pd.1970150816"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,8]]},"references-count":28,"journal-issue":{"issue":"8","published-print":{"date-parts":[[1995,8]]}},"alternative-id":["10.1002\/pd.1970150816"],"URL":"https:\/\/doi.org\/10.1002\/pd.1970150816","archive":["Portico"],"relation":{},"ISSN":["0197-3851","1097-0223"],"issn-type":[{"value":"0197-3851","type":"print"},{"value":"1097-0223","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,8]]}}}