{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T13:33:11Z","timestamp":1772544791833,"version":"3.50.1"},"reference-count":40,"publisher":"Wiley","issue":"13","license":[{"start":{"date-parts":[[2008,11,27]],"date-time":"2008-11-27T00:00:00Z","timestamp":1227744000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Department of Health Policy Research Programme"},{"DOI":"10.13039\/501100000272","name":"National Institute of Health Research","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2008,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe the prevalence, associated anomalies, prenatal diagnosis and survival of cases of gastroschisis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Data were extracted from the Northern Congenital Abnormality Survey (NorCAS) for cases delivered during 1997 to 2006.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 143 cases of gastroschisis were notified from 310 410 registered births. Ten (7%) gastroschisis cases were associated with other structural anomalies. The male to female ratio among isolated gastroschisis cases was 1:1.1 and 4:1 among non\u2010isolated cases. The total prevalence for isolated cases was 4.28 per 10 000 births (95% CI 3.56\u20135.01), and the overall live birth prevalence was 4.21 per 10 000 live births (95% CI 3.49\u20134.93). There was an increase in total prevalence during the ten years, although this increase did not reach statistical significance (\u03c7<jats:sup>2<\/jats:sup> test for trend = 0.996, p = 0.318). The maternal age\u2010specific prevalence was highest in the less than 20 years age group (18.6 per 10 000 births (95% CI 14.0\u201323.3)). 130 (97.7%) isolated cases resulted in a live birth; 122 (91.7%) infants were alive at age one year. The accuracy of prenatal diagnosis was high, with gastroschisis being detected in 130 (97.7%) isolated cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This population\u2010based study demonstrates a continued increase in gastroschisis, especially in young mothers. The accuracy of prenatal diagnosis was very high. Just over 90% of children born with gastroschisis survived. 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