{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,18]],"date-time":"2023-11-18T14:41:01Z","timestamp":1700318461172},"reference-count":7,"publisher":"Wiley","issue":"13","license":[{"start":{"date-parts":[[2002,1,8]],"date-time":"2002-01-08T00:00:00Z","timestamp":1010448000000},"content-version":"vor","delay-in-days":38,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2001,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This is a case report of the prenatal diagnosis of a <jats:italic>de novo<\/jats:italic> interstitial duplication of chromosome 2 (46,XX,dup(2)(p13p21) <jats:italic>de novo<\/jats:italic>) with an associated phenotypic abnormality. This chromosomal duplication is rare, only one has previously been described prenatally. Postnatal reports of similar duplications in this region have described associated dysmorphic features and significant neurodevelopmental delay. In our case, the only ultrasound finding was moderately severe ventriculomegaly. At post\u2010mortem, ventriculomegaly was confirmed and there was associated macrocephaly (head circumference above the 97th centile) with no dysmorphic features seen. Copyright \u00a9 2001 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/pd.216","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T16:30:43Z","timestamp":1030293043000},"page":"1169-1170","source":"Crossref","is-referenced-by-count":1,"title":["Duplication of chromosome 2 in association with ventriculomegaly \u2014 a case report"],"prefix":"10.1002","volume":"21","author":[{"given":"W. L.","family":"Martin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Pretlove","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Mercer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. C.","family":"Platt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Roberts","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Davison","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. D.","family":"Kilby","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,1,8]]},"reference":[{"issue":"3","key":"e_1_2_1_2_1","first-page":"174","article-title":"Partial duplication of the short arm of chromosome 2 [dup(2)(p13\u2013p21] associated with mental retardation and an Aarskog\u2010like phenotype","volume":"32","author":"Fryns JP","year":"1989","journal-title":"Ann Genet"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006254-199410000-00027"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1998.tb03696.x"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1970141121"},{"key":"e_1_2_1_6_1","first-page":"150","article-title":"Chromosomal findings in fetuses with ultrasonographically diagnosed ventriculomegaly","volume":"36","author":"Schwanitz G","year":"1993","journal-title":"Ann Genet"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(98)80003-3"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00286910"}],"container-title":["Prenatal Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.216","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pd.216","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,18]],"date-time":"2023-11-18T14:22:47Z","timestamp":1700317367000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/pd.216"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,12]]},"references-count":7,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2001,12]]}},"alternative-id":["10.1002\/pd.216"],"URL":"https:\/\/doi.org\/10.1002\/pd.216","archive":["Portico"],"relation":{},"ISSN":["0197-3851","1097-0223"],"issn-type":[{"value":"0197-3851","type":"print"},{"value":"1097-0223","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,12]]}}}