{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T15:39:50Z","timestamp":1791473990578,"version":"4.3.4"},"reference-count":27,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2009,10,7]],"date-time":"2009-10-07T00:00:00Z","timestamp":1254873600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"FIS","award":["PI070538"],"award-info":[{"award-number":["PI070538"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2009,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess the value of a prediction model for pre\u2010eclampsia (PE) in the first trimester (Ultrasound Obstet Gynecol 2007;30:742\u2013794) for the prediction of late (&gt;34 weeks) and early (\u226434 weeks) PE in a high\u2010risk population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Longitudinal study performed in 152 high\u2010risk pregnancies with at least one high\u2010risk condition: previous PE, hypertension, pregestational diabetes, renal disease, obesity, hyperlipidemia, autoimmune disorders, thrombophilia or recurrent pregnancy loss. Mean uterine artery pulsatility index at 11 to 13 + 6 weeks and a series of maternal variables were combined in order to obtain the estimated \u2018<jats:italic>a posteriori<\/jats:italic> risk for PE\u2019 in each woman. This risk for unaffected women was compared with that for patients who subsequently developed late and early PE. The performance of such approach was described by receiver\u2010operating characteristic curves.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Late PE developed in 13 (8.6%) pregnancies and early PE in seven (4.6%). The median \u2018<jats:italic>a posteriori<\/jats:italic> risk for PE\u2019 in the unaffected, late PE, and early PE groups was 0.62%, 1.22%, and 2.49% (<jats:italic>P<\/jats:italic> &lt; 0.01), respectively. For a false\u2010positive rate of 10%, the detection rates of late and early PE were 23.1 and 42.9%, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This referenced model shows a modest performance when applied to high\u2010risk women. Copyright \u00a9 2009 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.2383","type":"journal-article","created":{"date-parts":[[2009,10,7]],"date-time":"2009-10-07T15:42:13Z","timestamp":1254930133000},"page":"1123-1129","source":"Crossref","is-referenced-by-count":36,"title":["Application of a first\u2010trimester prediction model for pre\u2010eclampsia based on uterine arteries and maternal history in high\u2010risk 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