{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T18:50:31Z","timestamp":1769021431567,"version":"3.49.0"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,1,5]],"date-time":"2011-01-05T00:00:00Z","timestamp":1294185600000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2011,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the accuracy of amnionicity and chorionicity (A\/C) diagnosis of referral physicians and a tertiary care center as compared to histopathologic diagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A retrospective study of 289 multi\u2010fetal gestations was performed comparing A\/C diagnoses of referring physicians, a tertiary care center, and histopathology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Two hundred and eighty\u2010nine multi\u2010fetal pregnancies were referred for evaluation; only 43.6% (126\/289) carried an accurate diagnosis of A\/C before tertiary care center evaluation. The tertiary care center accurately identified A\/C in 94.8% (274\/289) overall and 100% in first trimester twins and triplets. Referrals with an unspecified A\/C diagnosis included 46.1% (113\/245) twins and 64.1% (25\/39) triplets.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Accurate diagnosis of A\/C can be obtained by the early assessment of key sonographic findings. Referral providers are less accurate at determining A\/C of mutifetal gestation when compared to a tertiary center, suggesting that an emphasis should be placed on enhancing these diagnostic skills in the general community or encouraging referral when diagnosis is ambiguous. 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