{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T01:58:20Z","timestamp":1791424700997,"version":"4.3.3"},"reference-count":69,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2011,9,14]],"date-time":"2011-09-14T00:00:00Z","timestamp":1315958400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2011,11]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>We conducted a meta\u2010analysis to assess the correlation of lung volume and liver position measured by magnetic resonance imaging (MRI) with survival until discharge in fetuses with isolated congenital diaphragmatic hernia (CDH).<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Systematic searches of MEDLINE and EMBASE from 1 January 1980 to 10 December 2010 were performed. Studies correlating total fetal lung volumes (TFLV, observed\/expected (O\/E) TFLV) and\/or liver position by fetal MRI to survival in expectantly managed fetuses with CDH were included. Data on the side of the defect, position of the liver, TFLV, O\/E TFLV, gestational age (GA) at MRI, GA and weight at birth were collected. Odds ratio (OR) for dichotomous data, mean differences (MD) or standardized mean differences (SMD) for continuous variables were determined using RevMan 5.0 software.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Nineteen studies (n\u2009=\u2009602 fetuses) were included. Survival was associated with left\u2010sided defects (OR 2.52; p\u2009=\u20090.01), \u201cliver down\u201d (OR 0.18; p\u2009&lt;\u20090.00001), a higher TFLV (MD 9.63; p\u2009&lt;\u20090.00001) and O\/E TFLV (SMD 0.98; p\u2009&lt;\u20090.00001) as well as higher birth weight (MD 146.60; p\u2009=\u20090.04). GA at MRI (MD 0.70) and GA at birth (MD 0.33) were not correlated with survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>MRI measurements of fetal lung volumes, liver position and side of the defect correlate well with neonatal survival in fetuses with isolated CDH. Copyright \u00a9 2011 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.2839","type":"journal-article","created":{"date-parts":[[2011,9,14]],"date-time":"2011-09-14T06:15:21Z","timestamp":1315980921000},"page":"1086-1096","source":"Crossref","is-referenced-by-count":83,"title":["The correlation between lung volume and liver herniation measurements by fetal MRI in isolated congenital diaphragmatic hernia: a systematic review and meta\u2010analysis of observational studies"],"prefix":"10.1002","volume":"31","author":[{"given":"Steffi","family":"Mayer","sequence":"first","affiliation":[{"name":"Centre for Surgical Technologies, Faculty of Medicine Katholieke Universiteit Leuven  B\u20103000 Leuven Belgium"},{"name":"Department of Paediatric Surgery University Hospital Leipzig  D\u201040103 Leipzig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp","family":"Klaritsch","sequence":"additional","affiliation":[{"name":"Centre for Surgical 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