{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T05:07:05Z","timestamp":1783055225764,"version":"3.54.6"},"reference-count":80,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2002,4,22]],"date-time":"2002-04-22T00:00:00Z","timestamp":1019433600000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2002,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Intrauterine growth restriction (IUGR) is a common complication in pregnancy and influences morbidity and mortality at all stages of life. Historically, the management of IUGR has been dependent on antenatal biophysical testing and umbilical artery Doppler studies. With recent Doppler studies of the fetal central circulation, including intracardiac flows and the ductus venosus, better timing of delivery to minimize morbidity may be possible. This review will provide the reader with tools to diagnose IUGR, more accurately date the IUGR pregnancy with poor dating criteria, and better assess the condition of the IUGR fetus. A brief review of animal models of IUGR is presented to demonstrate research directions for answering human clinical questions and potentially carrying therapeutic intervention from the bench to the bedside. Copyright \u00a9 2002 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/pd.311","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T23:24:15Z","timestamp":1030317855000},"page":"331-337","source":"Crossref","is-referenced-by-count":32,"title":["Intrauterine growth restriction (IUGR): biometric and Doppler assessment"],"prefix":"10.1002","volume":"22","author":[{"given":"Henry L.","family":"Galan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrico","family":"Ferrazzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John C.","family":"Hobbins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2002,4,22]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001703-199604000-00006"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0028-2243(94)90266-6"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(95)90424-7"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(99)70456-4"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(93)91224-A"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(99)70458-8"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1999.13030204.x"},{"key":"e_1_2_1_9_1","first-page":"17","article-title":"Some aspects of placental function in chronically heat\u2010stressed ewes","volume":"9","author":"Bell AW","year":"1987","journal-title":"J Dev Physiol"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.2000.279.3.H1256"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(98)00322-6"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1993.tb15139.x"},{"issue":"30","key":"e_1_2_1_13_1","first-page":"573","article-title":"Morphological changes in the utero\u2010placental bed in pregnancy hypertension","volume":"4","author":"Brosens IA","year":"1977","journal-title":"Clin Obstet Gynecol"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1977.tb12550.x"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1159\/000244352"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(97)70489-7"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1996.07010005.x"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(72)90317-1"},{"issue":"1","key":"e_1_2_1_19_1","first-page":"29","article-title":"Umbilical artery flow velocity waveform analysis and assessment of fetal oxygenation","volume":"26","author":"de Haan J","year":"1993","journal-title":"Gynakologe"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.1870090805"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.1870160402"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(96)70365-4"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1999.13050317.x"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-994114"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.1991.10.6.309"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/0029-7844(95)00021-I"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1053\/plac.1999.0395"},{"key":"e_1_2_1_28_1","article-title":"The temporal sequence of changes in fetal velocimetry indices for growth\u2010restricted fetuses","author":"Ferrazzi E","journal-title":"Am J Obstet Gynecol"},{"issue":"1","key":"e_1_2_1_29_1","first-page":"S127","article-title":"Umbilical venous blood flow is reduced in IUGR fetuses: a longitudinal study","volume":"182","author":"Ferrazzi E","year":"2000","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(86)90462-X"},{"key":"e_1_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-2115(98)00045-1"},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(98)70419-3"},{"key":"e_1_2_1_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(99)70098-0"},{"key":"e_1_2_1_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(99)70629-0"},{"key":"e_1_2_1_35_1","first-page":"135","article-title":"Umbilical artery flow velocity waveform analysis in normal ovine pregnancy and after carunculectomy","volume":"11","author":"Giles WB","year":"1989","journal-title":"J Dev Physiol"},{"key":"e_1_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/0301-5629(79)90014-0"},{"key":"e_1_2_1_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(89)90497-3"},{"key":"e_1_2_1_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(87)90111-6"},{"key":"e_1_2_1_39_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.1992.11.6.275"},{"key":"e_1_2_1_40_1","doi-asserted-by":"publisher","DOI":"10.1159\/000263759"},{"issue":"5","key":"e_1_2_1_41_1","first-page":"875","article-title":"Fetal femur length as a predictor of menstrual age: sonographically measured","volume":"138","author":"Hadlock RP","year":"1982","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_1_42_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.141.5.979"},{"key":"e_1_2_1_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(85)90298-4"},{"key":"e_1_2_1_44_1","first-page":"14","article-title":"Doppler velocimetry studies of the uterine artery in the early prediction of pre\u2010eclampsia and intra\u2010uterine growth retardation","volume":"42","author":"Harrington KF","year":"1991","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"e_1_2_1_45_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1996.07030182.x"},{"key":"e_1_2_1_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1999.tb08299.x"},{"key":"e_1_2_1_47_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1997.09030152.x"},{"key":"e_1_2_1_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(95)90161-2"},{"key":"e_1_2_1_49_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-994575"},{"key":"e_1_2_1_50_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016349609054684"},{"key":"e_1_2_1_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(94)90457-X"},{"key":"e_1_2_1_52_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1997.09040271.x"},{"key":"e_1_2_1_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(92)91683-2"},{"key":"e_1_2_1_54_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1998.12050339.x"},{"key":"e_1_2_1_55_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1999.14040250.x"},{"key":"e_1_2_1_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(11)90620-6"},{"key":"e_1_2_1_57_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1996.08020082.x"},{"key":"e_1_2_1_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0950-3552(88)80068-3"},{"key":"e_1_2_1_59_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003081-198912000-00004"},{"key":"e_1_2_1_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/0029-7844(95)00340-1"},{"key":"e_1_2_1_61_1","first-page":"277","article-title":"The influence of maternal undernutrition in ovine twin pregnancy on fetal growth and Doppler flow\u2010velocity waveforms","volume":"16","author":"Newnham JP","year":"1991","journal-title":"J Dev Physiol"},{"issue":"3","key":"e_1_2_1_62_1","first-page":"378","article-title":"Uterine artery Doppler flow velocity waveforms in the second trimester for the prediction of preeclampsia and fetal growth retardation","volume":"83","author":"North RA","year":"1994","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_63_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199303113281004"},{"key":"e_1_2_1_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(87)80019-4"},{"key":"e_1_2_1_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/0029-7844(95)00461-0"},{"key":"e_1_2_1_66_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1988.tb06481.x"},{"key":"e_1_2_1_67_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1996.08020087.x"},{"key":"e_1_2_1_68_1","first-page":"89","article-title":"Studies on experimental growth retardation in sheep. The effects of maternal hypoxemia","volume":"5","author":"Robinson JS","year":"1983","journal-title":"J Dev Physiol"},{"key":"e_1_2_1_69_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-994458"},{"key":"e_1_2_1_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(16)32283-9"},{"key":"e_1_2_1_71_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1993.tb14265.x"},{"issue":"2","key":"e_1_2_1_72_1","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1093\/oxfordjournals.humrep.a135966","article-title":"Intra\u2010observer, interobserver, interultrasound transducer and intercycle variation of colour Doppler assessment of uterine artery impedance","volume":"10","author":"Steer CV","year":"1995","journal-title":"Hum Reprod"},{"key":"e_1_2_1_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(97)80014-2"},{"key":"e_1_2_1_74_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.1995.14.5.343"},{"key":"e_1_2_1_75_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1985.tb01046.x"},{"key":"e_1_2_1_76_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1985.tb01044.x"},{"key":"e_1_2_1_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(87)90003-1"},{"key":"e_1_2_1_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-5629(96)00204-9"},{"key":"e_1_2_1_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(94)70285-3"},{"key":"e_1_2_1_80_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0412.1998.770607.x"},{"key":"e_1_2_1_81_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1997.09050330.x"}],"container-title":["Prenatal Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.311","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pd.311","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T13:36:43Z","timestamp":1694612203000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/pd.311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,4]]},"references-count":80,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2002,4]]}},"alternative-id":["10.1002\/pd.311"],"URL":"https:\/\/doi.org\/10.1002\/pd.311","archive":["Portico"],"relation":{},"ISSN":["0197-3851","1097-0223"],"issn-type":[{"value":"0197-3851","type":"print"},{"value":"1097-0223","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,4]]}}}