{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T20:47:04Z","timestamp":1760906824934},"reference-count":13,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2002,4,12]],"date-time":"2002-04-12T00:00:00Z","timestamp":1018569600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2002,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This report describes the prenatal findings in monozygotic twins with Costello syndrome. At 16 weeks one twin had 9\u2009mm of nuchal oedema: coarctation of the aorta was diagnosed after birth. At 22<jats:sup>5\/7<\/jats:sup> weeks relative macrocephaly, mild pyelectasia and moderate polyhydramnios were noted in both twins. In the following 4 weeks the polyhydramnios increased significantly without visualisation of filling of the stomach. Between 27<jats:sup>5\/7<\/jats:sup> and 30<jats:sup>2\/7<\/jats:sup> weeks a total of 9\u2009l amniotic fluid was drained and at 30<jats:sup>4\/7<\/jats:sup> weeks prelabor premature rupture of membranes (PPROM) occurred followed by premature labor and delivery. The neonatal period was complicated by growth retardation, deglutition problems, hypotonia, cardiac and respiratory problems. Both twins died on Day 57 because of respiratory insufficiency. Copyright \u00a9 2002 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/pd.333","type":"journal-article","created":{"date-parts":[[2004,6,30]],"date-time":"2004-06-30T16:02:40Z","timestamp":1088611360000},"page":"415-417","source":"Crossref","is-referenced-by-count":22,"title":["Prenatal findings in a monozygotic twin pregnancy with Costello syndrome"],"prefix":"10.1002","volume":"22","author":[{"given":"T.","family":"Van den Bosch","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Van Schoubroeck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. P.","family":"Fryns","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Naulaers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. 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