{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T04:08:45Z","timestamp":1695528525602},"reference-count":16,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2012,4,17]],"date-time":"2012-04-17T00:00:00Z","timestamp":1334620800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the influence of congenital heart disease (CHD) or congestive heart failure (CHF) on fetal urine production rate (UPR) and to establish normal reference intervals.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional study was performed on normal fetuses (<jats:italic>n<\/jats:italic>\u2009=\u2009314) and on fetuses with CHD (<jats:italic>n<\/jats:italic>\u2009=\u200949). CHD cases were divided into groups on the basis of heart function as defined by Huhta score: with CHF (<jats:italic>n<\/jats:italic>\u2009=\u200911) and without CHF (<jats:italic>n<\/jats:italic>\u2009=\u200938). Fetal bladder volume was measured by two\u2010dimensional as well as three\u2010dimensional ultrasound with the Virtual Organ Computer\u2010aided Analysis technique.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In normal fetuses, UPR increased with gestational age from a mean value of 4.5\u2009mL\/h at 21\u2009weeks to 66.5\u2009mL\/h at 40\u2009weeks. There were no significant differences in UPR between CHD cases without CHF and controls (<jats:italic>P<\/jats:italic>\u2009=\u20090.581). However, fetuses with CHF had decreased UPR values (Controls vs. CHF, <jats:italic>P<\/jats:italic>\u2009=\u20090.007) compared with the controls. The interobserver and intraobserver variability for assessment of UPR was better using three\u2010dimensional rather than two\u2010dimensional US.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Fetal UPR can be reproducibly measured by the Virtual Organ Computer\u2010aided Analysis technique. It appears that heart function, rather than CHD, affects fetal UPR. Fetal UPR may therefore be an additional indicator of CHF. \u00a9 2012 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.3852","type":"journal-article","created":{"date-parts":[[2012,4,18]],"date-time":"2012-04-18T03:50:51Z","timestamp":1334721051000},"page":"536-541","source":"Crossref","is-referenced-by-count":2,"title":["The effect of fetal congenital heart disease on <i>in utero<\/i> urine production rate"],"prefix":"10.1002","volume":"32","author":[{"given":"Jing\u2010Xian","family":"Xie","sequence":"first","affiliation":[{"name":"Department of Ultrasound The Second Affiliated Hospital of Fujian Medical University  Quanzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guo\u2010Rong","family":"Lv","sequence":"additional","affiliation":[{"name":"Department of Ultrasound The Second Affiliated Hospital of Fujian Medical University  Quanzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiu\u2010Yue","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Ultrasound The Second Affiliated Hospital of Fujian Medical University  Quanzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Hou","sequence":"additional","affiliation":[{"name":"Department of Ultrasound The Second Affiliated Hospital of Fujian Medical University  Quanzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,4,17]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.4038"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.7519"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2007.12.012"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.6440"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1447-0756.2009.01042.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-007-0360-2"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-010-1397-1"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0029-7844(96)00274-8"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.5218"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.5242"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2009.28.7.847"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-003-0591-3"},{"key":"e_1_2_6_14_1","first-page":"540","article-title":"Amniotic fluid volume assessment with the four\u2010quadrant technique at 36\u201342\u2009weeks' gestation","volume":"32","author":"Phelan JP","year":"1987","journal-title":"J Reprod Med"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2001.00397.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1785"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-008-0732-z"}],"container-title":["Prenatal Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.3852","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pd.3852","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T14:29:19Z","timestamp":1695479359000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/pd.3852"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4,17]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["10.1002\/pd.3852"],"URL":"https:\/\/doi.org\/10.1002\/pd.3852","archive":["Portico"],"relation":{},"ISSN":["0197-3851","1097-0223"],"issn-type":[{"value":"0197-3851","type":"print"},{"value":"1097-0223","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,4,17]]}}}