{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:13:56Z","timestamp":1772118836463,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2012,5,15]],"date-time":"2012-05-15T00:00:00Z","timestamp":1337040000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2012,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate perinatal outcomes of fetal echogenic bowel (FEB).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>This is a retrospective observational study of FEB cases from Jan 2005\u2013Dec 2010. Data from ultrasound and fetal medicine investigations, uterine artery Doppler (UAD), intra\u2010partum care and neonatal outcome were obtained from Fetal Medicine, Obstetric and Neonatal Databases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There were 139 cases presenting at 21\n                      <jats:sup>+5<\/jats:sup>\n                      (15\n                      <jats:sup>+1<\/jats:sup>\n                      \u201335\n                      <jats:sup>+5<\/jats:sup>\n                      )\u2009weeks gestation. Overall, 106\/139 (76.2%) were live born (LB), 8\/139 (5.8%) were complicated by intra\u2010uterine deaths (IUD), 11\/139 (7.9%) had termination of pregnancy (TOP) and 14\/139 (10.1%) were lost to follow\u2010up after 28\u2009weeks gestation. Six had chromosomal\/genetic abnormalities, two had congenital cytomegalovirus, none had cystic fibrosis.Uterine artery Doppler was normal in 106\/130 (81.5%) cases. In this group, there were no cases of fetal growth restriction (FGR), 95\/106 (89.6%) were LB, 1\/106 (0.94%) had an IUD. In the abnormal UAD group, 17\/24 (70.1%) developed FGR, 11\/24 (45.8%) were LB, 4\/24 (16.7%) had TOP, 7\/24 (29.2%) had IUD.In total, 20\/106 (18.9%) live births were admitted for specialist neonatal care, 12\/20 (60%) for prematurity. Only one had primary bowel pathology.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Pregnancies with FEB and screen positive UAD are at risk of adverse perinatal outcome. Primary bowel pathology is rare following the finding of FEB. \u00a9 2012 John Wiley &amp; Sons, Ltd.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pd.3898","type":"journal-article","created":{"date-parts":[[2012,5,15]],"date-time":"2012-05-15T22:27:39Z","timestamp":1337120859000},"page":"758-764","source":"Crossref","is-referenced-by-count":17,"title":["Perinatal outcomes of fetal echogenic bowel"],"prefix":"10.1002","volume":"32","author":[{"given":"Esha","family":"Saha","sequence":"first","affiliation":[{"name":"Department of Fetal Medicine, St. Mary's Hospital Imperial College Healthcare NHS Trust London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward William Samuel","family":"Mullins","sequence":"additional","affiliation":[{"name":"Centre for Fetal Care, Queen Charlotte's and Chelsea Hospital Imperial College Healthcare NHS Trust London UK"},{"name":"Imperial College London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gowrishankar","family":"Paramasivam","sequence":"additional","affiliation":[{"name":"Centre for Fetal Care, Queen Charlotte's and Chelsea Hospital Imperial College Healthcare NHS Trust London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sailesh","family":"Kumar","sequence":"additional","affiliation":[{"name":"Centre for Fetal Care, Queen Charlotte's and Chelsea Hospital Imperial College Healthcare NHS Trust London UK"},{"name":"Imperial College London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorin","family":"Lakasing","sequence":"additional","affiliation":[{"name":"Department of Fetal Medicine, St. Mary's Hospital Imperial College Healthcare NHS Trust London UK"},{"name":"Centre for Fetal Care, Queen Charlotte's and Chelsea Hospital Imperial College Healthcare NHS Trust London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,5,15]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"592","article-title":"Fetal soft markers in obstetric ultrasound","volume":"162","author":"Van der Hof MC","year":"2005","journal-title":"J Obstet Gynecol Can"},{"issue":"12","key":"e_1_2_5_3_1","first-page":"964","article-title":"Fetal echogenic bowel by ultrasound: what is the clinical significance?","volume":"146","author":"Bashiri A","year":"2007","journal-title":"Harefuah"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2000.00241.x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2001.117671"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1159\/000020914"},{"key":"e_1_2_5_7_1","first-page":"647","article-title":"Is fetal hyperechoic bowel on second\u2010trimester sonogram an indicator for amniocentesis?","volume":"83","author":"Bromley B","year":"1994","journal-title":"Obstet Gynecol"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767050903551442"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(99)00286-0"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.5314"},{"issue":"5","key":"e_1_2_5_11_1","doi-asserted-by":"crossref","first-page":"649","DOI":"10.47102\/annals-acadmedsg.V32N5p649","article-title":"A case series of gastrointestinal abnormalities in fetuses with echogenic bowel detected during the antenatal period","volume":"32","author":"Tan HH","year":"2003","journal-title":"Ann Acad Med Singapore"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1247523"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1242"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ogx.0000216518.85796.88"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.787"}],"container-title":["Prenatal Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.3898","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.3898","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pd.3898","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,27]],"date-time":"2025-03-27T23:41:56Z","timestamp":1743118916000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/pd.3898"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,5,15]]},"references-count":14,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["10.1002\/pd.3898"],"URL":"https:\/\/doi.org\/10.1002\/pd.3898","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.717953511.793459062","asserted-by":"object"}]},"ISSN":["0197-3851","1097-0223"],"issn-type":[{"value":"0197-3851","type":"print"},{"value":"1097-0223","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,5,15]]}}}