{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T07:10:34Z","timestamp":1780384234999,"version":"3.54.1"},"reference-count":23,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2012,7,24]],"date-time":"2012-07-24T00:00:00Z","timestamp":1343088000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2012,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the fetal cardiac function by modified myocardial performance index (Mod\u2010MPI) in pregnant diabetic patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Modified myocardial performance index was measured in fetuses of patients with diabetes (DM) between 30 and 40 weeks of gestation. The isovolumetric contraction time, isovolumetric relaxation time and ejection time were measured. Mod\u2010MPI was calculated as (isovolumetric contraction time\u2009+\u2009isovolumetric relaxation time)\/ejection time. Results were analyzed by using one\u2010way analysis of variance (post hoc Bonferroni correction), Chi\u2010square and Student's test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Modified myocardial performance index values of fetuses from DM mothers were significantly higher than controls (0.43 vs 0.37, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001), and it was not different between gestational versus pregestational DM (0.42 vs 0.45, <jats:italic>P<\/jats:italic>\u2009=\u20090.18). Mod\u2010MPI was also higher in the presence of polyhydramnios (0.49 vs 0.41, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001), insulin use (0.46 vs 0.40, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05), and large for gestational age fetuses (0.49 vs 0.40, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001). There were no significant differences in Mod\u2010MPI between newborns with versus without neonatal complications such as hypoglycemia or polycythemia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In fetuses of DM mothers, evaluation of the Mod\u2010MPI identifies those with worse maternal disease and large fetal size. \u00a9 2012 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.3937","type":"journal-article","created":{"date-parts":[[2012,7,24]],"date-time":"2012-07-24T10:12:53Z","timestamp":1343124773000},"page":"943-948","source":"Crossref","is-referenced-by-count":38,"title":["Fetal evaluation of the modified\u2010myocardial performance index in pregnancies complicated by diabetes"],"prefix":"10.1002","volume":"32","author":[{"given":"Horacio","family":"Figueroa","sequence":"first","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology and Laboratory of Reproductive Biology Universidad de Los Andes  Chile"},{"name":"Department of Maternal\u2010Fetal Medicine, Cl\u00ednica Davila  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Carolna","family":"Silva","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology and Laboratory of Reproductive Biology Universidad de Los Andes  Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristian","family":"Kottmann","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology and Laboratory of Reproductive Biology Universidad de Los Andes  Chile"},{"name":"Department of Maternal\u2010Fetal Medicine, Cl\u00ednica Davila  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Viguera","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology and Laboratory of Reproductive Biology Universidad de Los Andes  Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ignacio","family":"Valenzuela","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology and Laboratory of Reproductive Biology Universidad de Los Andes  Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edgar","family":"Hernandez\u2010Andrade","sequence":"additional","affiliation":[{"name":"Clinic Institute of Gynecology, Obstetrics and Neonatology (ICGON), Hospital Clinic, and Fetal and Perinatal Medicine Group, Institutd' Investigacions Biomediques Augus Pii Sunyer (IDIBAPS) Universidad de Barcelona  Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduard","family":"Gratacos","sequence":"additional","affiliation":[{"name":"Clinic Institute of Gynecology, Obstetrics and Neonatology (ICGON), Hospital Clinic, and Fetal and Perinatal Medicine Group, Institutd' Investigacions Biomediques Augus Pii Sunyer (IDIBAPS) Universidad de Barcelona  Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Antonio","family":"Arraztoa","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology and Laboratory of Reproductive Biology Universidad de Los Andes  Chile"},{"name":"Department of Maternal\u2010Fetal Medicine, Cl\u00ednica Davila  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebasti\u00e1n E.","family":"Illanes","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology and Laboratory of Reproductive Biology Universidad de Los Andes  Chile"},{"name":"Department of Maternal\u2010Fetal Medicine, Cl\u00ednica Davila  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,7,24]]},"reference":[{"issue":"6","key":"e_1_2_8_2_1","first-page":"357","article-title":"New index of combined systolic and diastolic myocardial performance: a simple and reproducible measure of cardiac function\u2010\u2010a study in normals and dilated cardiomyopathy","volume":"26","author":"Tei C","year":"1995","journal-title":"J Cardiol"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1442-200x.1999.01155.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1959"},{"issue":"6","key":"e_1_2_8_5_1","first-page":"473","article-title":"Study of global left atrial shortening in fetuses of diabetic mothers","volume":"83","author":"Zielinsky P","year":"2004","journal-title":"Arq Bras Cardiol"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(96)00202-1"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.3947"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(95)91339-4"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.88"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.3957"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000073191"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(91)90526-W"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9136(199807)15:7<539::AID-DIA668>3.0.CO;2-S"},{"issue":"10","key":"e_1_2_8_14_1","first-page":"1155","article-title":"A national birth weight distribution curve according to gestational age in Chile from 1993 to 2000","volume":"132","author":"Gonzalez RP","year":"2004","journal-title":"Rev Med Chil"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(00)01020-6"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0095-5108(18)30276-8"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2000-7296"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.321.7258.405"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000012466.50373.E8"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2003.10.022"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2005.083840"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000023900.58293.FE"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2003.11.004"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2005.076885"}],"container-title":["Prenatal Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.3937","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.3937","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pd.3937","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T12:54:09Z","timestamp":1695473649000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/pd.3937"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7,24]]},"references-count":23,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["10.1002\/pd.3937"],"URL":"https:\/\/doi.org\/10.1002\/pd.3937","archive":["Portico"],"relation":{},"ISSN":["0197-3851","1097-0223"],"issn-type":[{"value":"0197-3851","type":"print"},{"value":"1097-0223","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,7,24]]}}}