{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T16:53:43Z","timestamp":1783443223650,"version":"3.54.6"},"reference-count":52,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2012,7,23]],"date-time":"2012-07-23T00:00:00Z","timestamp":1343001600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2012,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine the association between Doppler changes in the fetal vertebral (VA), middle cerebral (MCA), and umbilical arteries (UA) and severity of growth restriction (FGR) in fetuses delivered after 34\u2009weeks.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Five hundred seventy\u2010one Doppler examinations of the VA, MCA, and UA were performed between 26 and 41\u2009weeks of gestation. Values were converted into multiples of the median and divided into birth weight (BW) categories: BW&gt;P10<jats:sup>th<\/jats:sup>, BW&lt;P10<jats:sup>th<\/jats:sup>, BW&lt;P5th, and BW&lt;P3<jats:sup>rd<\/jats:sup>. Differences were evaluated and multivariate logistic regression models plus receiver\u2010operating characteristic curves were calculated to determine the accuracy of Doppler measurements for the prediction of FGR percentiles.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The UA pulsatility index (PI) was significant predicting BW&lt;P10<jats:sup>th<\/jats:sup> and BW&lt;P3<jats:sup>rd<\/jats:sup>, the VA PI was significant predicting BW&lt;P5<jats:sup>th<\/jats:sup> and BW&lt;P3<jats:sup>rd<\/jats:sup>. Finally, the MCA PI was not predictive of any degree of severity of FGR. In addition, only VA and UA differences were statistically significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In fetuses delivered after 34\u2009weeks, mild degrees of growth restriction are better associated with high UA PI whereas severe degrees are associated with low VA PI but not with low MCA PI. \u00a9 2012 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.3941","type":"journal-article","created":{"date-parts":[[2012,7,23]],"date-time":"2012-07-23T10:09:45Z","timestamp":1343038185000},"page":"960-967","source":"Crossref","is-referenced-by-count":20,"title":["Doppler changes in the vertebral, middle cerebral, and umbilical arteries in fetuses delivered after 34\u2009weeks: relationship to severity of growth restriction"],"prefix":"10.1002","volume":"32","author":[{"given":"Jos\u00e9","family":"Morales Rosell\u00f3","sequence":"first","affiliation":[{"name":"Servicio de Obstetricia y Ginecolog\u00eda Hospital Universitario y Polit\u00e9cnico La Fe  Valencia Spain"},{"name":"Servicio de Obstetricia y Ginecolog\u00eda Hospital de La Plana  Villarreal Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Herv\u00e1s Mar\u00edn","sequence":"additional","affiliation":[{"name":"Unidad de Bioestad\u00edstica Instituto de Investigaci\u00f3n Sanitaria La Fe  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Fillol Crespo","sequence":"additional","affiliation":[{"name":"Servicio de Obstetricia y Ginecolog\u00eda Hospital de La Plana  Villarreal Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfredo","family":"Perales Mar\u00edn","sequence":"additional","affiliation":[{"name":"Servicio de Obstetricia y Ginecolog\u00eda Hospital Universitario y Polit\u00e9cnico La Fe  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,7,23]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwn233"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.9041"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000253847"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000323548"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.4084"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2002.00758.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.7588"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-3806(03)00103-2"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.10069"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000337365"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2012.31.7.1003"},{"key":"e_1_2_5_13_1","unstructured":"Morales Rosell\u00f3J Peralta LLorensN Lopez FraileS.Doppler study of the fetal vertebral and middle cerebral arteries in fetuses with normal and increased umbilical artery resistance indices. 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