{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T19:10:24Z","timestamp":1722885024735},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,2,6]],"date-time":"2013-02-06T00:00:00Z","timestamp":1360108800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>The aim of this study was to develop a simple clinical algorithm for prediction of donor and recipient death using \u2018yes'or \u2018no\u2019 questions through the process of recursive partitioning for patients undergoing laser therapy for twin to twin transfusion syndrome (TTTS). The intent was to identify a subset of patients with very high specificity to whom clinical decisions would be simplified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Secondary analysis of data retrospectively collected from laser procedures was performed for TTTS at NAFTNet centers from 2002 to 2009. Preoperative factors associated with donor and recipient death were identified by recursive partitioning regression analysis. Classification And Regression Trees (CARTs) were developed to refine specificity for prediction of death.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 466 TTTS patients from eight centers. CARTs were obtained for prediction of donor death. Improved specificity was achieved through recursive partitioning as demonstrated in receiver operator characteristic curves for prediction of death of the donor. There was less than optimal predictive ability for prediction of death in the recipient, as demonstrated by lack of generation of CARTs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Recursive partitioning improves the specificity and refines the prediction of donor fetal and neonatal demise in TTTS treated with laser therapy. This has the potential to improve therapeutic choices and refine counseling regarding outcomes. \u00a9 2013 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.4059","type":"journal-article","created":{"date-parts":[[2013,2,6]],"date-time":"2013-02-06T07:10:26Z","timestamp":1360134626000},"page":"279-283","source":"Crossref","is-referenced-by-count":4,"title":["Laser ablation of placental anastomoses in twin\u2010to\u2010twin transfusion syndrome: preoperative predictors of death by recursive partitioning"],"prefix":"10.1002","volume":"33","author":[{"given":"Daniel W.","family":"Skupski","sequence":"first","affiliation":[{"name":"Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology Weill Cornell College of Medicine  New York NY USA"},{"name":"New York Hospital Queens  Flushing NY 11355 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francois I.","family":"Luks","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery Alpert Medical School of Brown University and the Fetal Treatment Program of New England  Providence RI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramesha","family":"Papanna","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology Yale University School of Medicine  New Haven CT USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Walker","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Evergreen Hospital  Seattle WA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Bebbington","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Gynecology and Reproductive Sciences University of Texas Medical School at Houston and Children's Memorial Hermann Hospital  Houston TX 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