{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,8]],"date-time":"2023-10-08T11:15:16Z","timestamp":1696763716691},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,2,25]],"date-time":"2013-02-25T00:00:00Z","timestamp":1361750400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To study signal intensity (SI) of the fetal liver by MRI in\u2010phase and out\u2010of\u2010phase over gestational age (GA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 91 pregnant women from 19 to 38 gestational weeks were imaged using MRI. Liver\u2010to\u2010spleen SI ratios of the right and left fetal liver lobes on in\u2010phase and out\u2010of\u2010phase were measured, calculated, and compared with each other. Curves of liver\u2010to\u2010spleen SI ratio of the right and left liver lobe were plotted by GA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Liver\u2010to\u2010spleen SI ratio of the right lobe on in\u2010phase was different from that of the left liver lobe (<jats:italic>t<\/jats:italic>\u2009=\u20093.95; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). A statistically significant difference was also found for out\u2010of\u2010phase SI ratios (<jats:italic>t<\/jats:italic>\u2009=\u20093.69; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Curves of liver\u2010to\u2010spleen SI ratio of the fetal liver on in\u2010phase and out\u2010of\u2010phase showed changes against GA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Liver\u2010to\u2010spleen SI ratio is different between the right and left liver lobe, which probably results from the different blood supply. Curves of liver\u2010to\u2010spleen SI ratios between 19 to 38 gestational weeks reflect the changes of decreasing function of blood production by fetal liver. In\u2010phase and out\u2010of\u2010phase may have clinical use in the early detection of disordered fetal growth and metabolism. \u00a9 2013 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.4075","type":"journal-article","created":{"date-parts":[[2013,2,26]],"date-time":"2013-02-26T04:47:40Z","timestamp":1361854060000},"page":"313-317","source":"Crossref","is-referenced-by-count":4,"title":["Signal intensity changes of the fetal liver on MRI in\u2010phase and out\u2010of\u2010phase sequence"],"prefix":"10.1002","volume":"33","author":[{"given":"Xiaobing","family":"Li","sequence":"first","affiliation":[{"name":"Department of Radiology Nanjing Medical University Affiliated Suzhou Hospital  Suzhou Jiangsu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter C.","family":"Brugger","sequence":"additional","affiliation":[{"name":"Center of Anatomy and Cell Biology, Integrative Morphology Group Medical University of Vienna  Vienna 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