{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T21:10:44Z","timestamp":1788469844300,"version":"build-2803163510"},"reference-count":19,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,3,20]],"date-time":"2013-03-20T00:00:00Z","timestamp":1363737600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aimed to analyze success rates and pregnancy outcomes of amniopatch procedures for previable iatrogenic preterm prelabour rupture of the membranes (PPROM) with associated oligohydramnios.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective analysis of amniopatch procedures performed at the University Hospitals Leuven, Belgium, and the Mount Sinai Hospital Toronto, Canada. Cases were analyzed overall and in two sub\u2010groups: PPROM after a needle\u2010based procedure (NP group, <jats:italic>n<\/jats:italic>\u2009=\u200913) or after fetoscopic intervention (FI group, <jats:italic>n<\/jats:italic>\u2009=\u200911). Complete technical success was defined as cessation of leakage and normalization of amniotic fluid volume, partial success as cessation of leakage, or re\u2010establishment of volume. Further outcomes were pregnancy duration and outcome, fetal\/neonatal morbidity and mortality, and maternal morbidity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Gestational age at amniopatch was comparable in both groups (NP: 20.1, FI: 21.0\u2009weeks). Amniopatch was completely and partially successful in 29% (NP: 31%; FI: 27%) and 29% (NP: 15%; FI: 45%), respectively. Mean gestational age at delivery was 27.5\u2009weeks (NP: 25.5; FI: 29.4\u2009weeks). Overall neonatal survival was 17\/31 (55%) (NP: 4\/13 (31%), FI: 13\/18 (72%); <jats:italic>p<\/jats:italic>\u2009=\u2009.02). Chorioamnionitis occurred in three cases, two associated with maternal sepsis. Severe neonatal morbidity occurred in two survivors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Amniopatch for iPPROM was successful in 58%, with an overall live birth rate of 68% and survival to discharge of 55%. \u00a9 2013 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.4080","type":"journal-article","created":{"date-parts":[[2013,3,20]],"date-time":"2013-03-20T06:20:56Z","timestamp":1363760456000},"page":"391-396","source":"Crossref","is-referenced-by-count":27,"title":["Amniopatch procedure after previable iatrogenic rupture of the membranes: a two\u2010center review"],"prefix":"10.1002","volume":"33","author":[{"given":"Jute","family":"Richter","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology University Hospitals of Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Henry","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit Mount Sinai Hospital, University of Toronto  Toronto Canada"},{"name":"School of Women's and Children's Health University of New South Wales  Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greg","family":"Ryan","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit Mount Sinai Hospital, University of Toronto  Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"DeKoninck","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University Hospitals of Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liesbeth","family":"Lewi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University Hospitals of Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Deprest","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University Hospitals of Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,3,20]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"520","article-title":"Genetic amniocentesis \u2013 indications and risks","volume":"35","author":"Tabor A","year":"1988","journal-title":"Dan Med Bull"},{"issue":"9098","key":"e_1_2_8_3_1","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/S0140-6736(97)12346-7","article-title":"Randomised trial to assess safety and fetal outcome of early and midtrimester amniocentesis. 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