{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T08:30:08Z","timestamp":1723105808191},"reference-count":9,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,1,13]],"date-time":"2014-01-13T00:00:00Z","timestamp":1389571200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Transient abnormal myelopoiesis (TAM) is a relatively common finding in children with Down syndrome but has also been diagnosed prenatally, most often presenting with fetal hepatosplenomegaly. We report a case of TAM with hepatosplenomegaly found on ultrasound and associated with an increased amniotic fluid \u0394 OD 450 value. TAM is most commonly transient but can be associated with fatality and therefore should be considered in the differential diagnosis when fetal hepatosplenomegaly is found on ultrasound. Amniocentesis with chromosomal analysis and a \u0394 OD 450 may aid in diagnosing TAM and predicting the severity of the liver involvement. \u00a9 2013 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/pd.4299","type":"journal-article","created":{"date-parts":[[2013,12,19]],"date-time":"2013-12-19T07:07:02Z","timestamp":1387436822000},"page":"299-301","source":"Crossref","is-referenced-by-count":3,"title":["Elevated delta OD 450 due to transient abnormal myelopoiesis in a Down syndrome fetus with hepatosplenomegaly on ultrasound"],"prefix":"10.1002","volume":"34","author":[{"given":"Abigail","family":"Mancuso","sequence":"first","affiliation":[{"name":"Division of Perinatal Care, Department of Obstetrics and Gynecology University of Iowa Hospitals and Clinics  Iowa City IA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asha","family":"Rijhsinghani","sequence":"additional","affiliation":[{"name":"Division of Perinatal Care, Department of Obstetrics and Gynecology University of Iowa Hospitals and Clinics  Iowa City IA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,1,13]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1738"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0146-0005(97)80025-0"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-04-350017"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0223(199807)18:7<731::AID-PD322>3.0.CO;2-A"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-004-1452-7"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2001.00362.x"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1718"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2009.10.2.190"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-10-118810"}],"container-title":["Prenatal Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.4299","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pd.4299","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T14:46:50Z","timestamp":1696517210000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/pd.4299"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,13]]},"references-count":9,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,3]]}},"alternative-id":["10.1002\/pd.4299"],"URL":"https:\/\/doi.org\/10.1002\/pd.4299","archive":["Portico"],"relation":{},"ISSN":["0197-3851","1097-0223"],"issn-type":[{"value":"0197-3851","type":"print"},{"value":"1097-0223","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1,13]]}}}