{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T05:42:16Z","timestamp":1696570936304},"reference-count":14,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,4,27]],"date-time":"2014-04-27T00:00:00Z","timestamp":1398556800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:p><jats:bold>What's already known about this topic?<\/jats:bold>  \n<jats:list list-type=\"bullet\">\n<jats:list-item><jats:p>Prenatal bilateral adrenal calcifications are a rare prenatal finding.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Adrenal calcifications may be seen with intrauterine infections, tumor, or in Wolman disease. Risk factors for adrenal calcifications include large birth weight, hypoxia, septicemia, coagulation defects, and thromboembolism.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>The association of adrenal calcifications and proteinuria has been published in two reports of four different patients.<\/jats:p><\/jats:list-item><\/jats:list><\/jats:p><jats:p><jats:bold>What does this study add?<\/jats:bold>  \n<jats:list list-type=\"bullet\">\n<jats:list-item><jats:p>We propose that the constellation of bilateral adrenal calcifications, micropenis, testicular dysfunction, increased fetal nuchal translucency, and congenital nephrotic syndrome represents a new clinical entity.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>The consanguinity in this family suggests an autosomal recessive inheritance of this disease.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>This entity should be considered in the differential diagnosis of bilateral adrenal calcifications.<\/jats:p><\/jats:list-item><\/jats:list><\/jats:p>","DOI":"10.1002\/pd.4344","type":"journal-article","created":{"date-parts":[[2014,2,24]],"date-time":"2014-02-24T17:55:58Z","timestamp":1393264558000},"page":"608-611","source":"Crossref","is-referenced-by-count":2,"title":["Prenatal bilateral adrenal calcifications, hypogonadism, and nephrotic syndrome: beyond Wolman disease"],"prefix":"10.1002","volume":"34","author":[{"given":"Nira","family":"Schreyer\u2010Shafir","sequence":"first","affiliation":[{"name":"Institute of Human Genetics Meir Medical Center  Kfar Saba Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rivka","family":"Sukenik\u2010Halevy","sequence":"additional","affiliation":[{"name":"Institute of Human Genetics Meir Medical Center  Kfar Saba Israel"},{"name":"Ultrasound Unit, Department of Obstetrics and Gynecology Meir Medical Center  Kfar Saba Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronnie","family":"Tepper","sequence":"additional","affiliation":[{"name":"Ultrasound Unit, Department of Obstetrics and Gynecology Meir Medical Center  Kfar Saba Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Schmuel","family":"Arnon","sequence":"additional","affiliation":[{"name":"Department of Neonatology Meir Medical Center  Kfar Saba Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Itta","family":"Litmanovitch","sequence":"additional","affiliation":[{"name":"Department of Neonatology Meir Medical Center  Kfar Saba Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alon","family":"Eliakim","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Meir Medical Center  Kfar Saba Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Avishalom","family":"Pommeranz","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Meir Medical Center  Kfar Saba Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark David","family":"Ludman","sequence":"additional","affiliation":[{"name":"Institute of Human Genetics Meir Medical Center  Kfar Saba Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annick","family":"Raas\u2010Rothschild","sequence":"additional","affiliation":[{"name":"Institute of Human Genetics Meir Medical Center  Kfar Saba Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,4,27]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1542\/peds.28.5.742","article-title":"Primary familial xanthomatosis with involvement and calcification of the adrenals. Report of two more cases in siblings of a previously described infant","volume":"28","author":"Wolman M","year":"1961","journal-title":"Pediatrics"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-200307000-00031"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.91.7.2718"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-200x.2005.02139.x"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-1004(1997)9:3<209::AID-HUMU2>3.0.CO;2-2"},{"key":"e_1_2_4_7_1","first-page":"135","article-title":"Calcification of the adrenal gland and cytomegalovirus infection in early childhood","volume":"28","author":"Magnin D","year":"1973","journal-title":"Helv Paediatr Acta"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02390405"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-0891"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2001.00454.x"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2013.01.010"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0223(200102)21:2<81::AID-PD1>3.0.CO;2-8"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.121"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00858433"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02724410"}],"container-title":["Prenatal Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.4344","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pd.4344","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T05:26:22Z","timestamp":1696483582000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/pd.4344"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4,27]]},"references-count":14,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["10.1002\/pd.4344"],"URL":"https:\/\/doi.org\/10.1002\/pd.4344","archive":["Portico"],"relation":{},"ISSN":["0197-3851","1097-0223"],"issn-type":[{"value":"0197-3851","type":"print"},{"value":"1097-0223","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,4,27]]}}}