{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T08:54:57Z","timestamp":1767084897029},"reference-count":43,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,3,19]],"date-time":"2014-03-19T00:00:00Z","timestamp":1395187200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aimed to analyze perinatal outcome in monoamniotic (MA) pregnancies that underwent antenatal surgical interventions for fetal complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Review of all MA pregnancies treated with antenatal surgical interventions in three fetal treatment centers between 2000 and 2013. Indications were twin\u2013twin transfusion syndrome, twin reversed arterial perfusion sequence, discordant anomalies, or elective reduction. We analyzed associations between indication, type of intervention, perinatal survival, and gestational age (GA) at birth and compared our results with a systematic review of the literature.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifty\u2010eight MA pregnancies were included. Median GA at treatment was 18.0\u2009weeks (range: 13.1\u201333.0). Procedures included cord coagulation plus transection (<jats:italic>n<\/jats:italic>\u2009=\u200942), cord coagulation without transection (<jats:italic>n<\/jats:italic>\u2009=\u20097), laser coagulation of placental anastomoses (<jats:italic>n<\/jats:italic>\u2009=\u20097), and one case each with interstitial laser and radiofrequency ablation. Median GA at birth was 34\u2009weeks (range 16.0\u201341.0), and 75% (53\/71) of fetuses intended to survive indeed survived. Literature review included 20 articles, reporting on a total of 45 cases of surgically treated MA pregnancies, showing similar outcome results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We present the largest series concerning surgical interventions in complicated MA pregnancies. Despite being rare in experienced hands, a 75% survival is achieved. Collaboration between centers, data sharing, and benchmarking may further improve outcome. \u00a9 2014 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.4353","type":"journal-article","created":{"date-parts":[[2014,3,4]],"date-time":"2014-03-04T14:59:06Z","timestamp":1393945146000},"page":"586-591","source":"Crossref","is-referenced-by-count":30,"title":["Fetal surgery in complicated monoamniotic pregnancies: case series and systematic review of the literature"],"prefix":"10.1002","volume":"34","author":[{"given":"Suzanne H.\u2009P.","family":"Peeters","sequence":"first","affiliation":[{"name":"Department of Obstetrics Leiden University Medical Center  Leiden The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roland","family":"Devlieger","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University hospitals of KU Leuven  Leuven 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