{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T21:57:00Z","timestamp":1786571820104,"version":"build-2736575974"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,12,29]],"date-time":"2014-12-29T00:00:00Z","timestamp":1419811200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To test the hypothesis that the pulmonary vein pulsatility index (PVPI) is higher in fetuses with growth restriction (IUGR) than in normal fetuses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty\u2010two fetuses with IUGR and twenty\u2010one (21) fetuses with appropriate growth for gestational age from healthy mothers were studied. PVPI was calculated by Doppler echocardiography [maximal velocity (systolic or diastolic peak)\u2009\u2212\u2009pre\u2010systolic peak\u2009\/\u2009mean velocity]. Obstetric ultrasound was used to assess fetal biometry and Doppler to assess the uterine, umbilical and middle cerebral arteries PI. Statistical analysis used <jats:italic>t<\/jats:italic> test and Pearson's correlation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean gestational age was 31.5\u2009+\/\u2212\u20092.1\u2009weeks in the control group and 31.4\u2009+\/\u2212\u20093.1\u2009weeks in IUGR (<jats:italic>P<\/jats:italic>\u2009=\u20090.91). The PI of uterine and umbilical arteries were higher in IUGR than in controls (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Mean PVPI in IUGR fetuses was 1.31\u2009+\/\u2212\u20090.41, and in controls it was 0.83\u2009+\/\u2212\u20090.11 (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The pulsatility index of pulmonary venous flow in fetuses with growth restriction is higher than in normal fetuses, probably as a result of left atrial dynamics alteration secondary or not to fetal left ventricular diastolic dysfunction. \u00a9 2014 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.4529","type":"journal-article","created":{"date-parts":[[2014,11,12]],"date-time":"2014-11-12T02:49:28Z","timestamp":1415760568000},"page":"249-253","source":"Crossref","is-referenced-by-count":12,"title":["Dynamics of pulmonary venous flow in fetuses with intrauterine growth restriction"],"prefix":"10.1002","volume":"35","author":[{"given":"Nathalie J. M.","family":"Bravo\u2010Valenzuela","sequence":"first","affiliation":[{"name":"Fetal Cardiology Unit Institute of Cardiology  Porto Alegre RS Brazil"},{"name":"University of Taubate  Taubate S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9268-1450","authenticated-orcid":false,"given":"Paulo","family":"Zielinsky","sequence":"additional","affiliation":[{"name":"Fetal Cardiology Unit Institute of Cardiology  Porto Alegre RS Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James C.","family":"Huhta","sequence":"additional","affiliation":[{"name":"All Children's Hospital Johns Hopkins University  St. Petersburg FL United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greg\u00f3rio L.","family":"Acacio","sequence":"additional","affiliation":[{"name":"University of Taubate  Taubate S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz H.","family":"Nicoloso","sequence":"additional","affiliation":[{"name":"Fetal Cardiology Unit Institute of Cardiology  Porto Alegre RS Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Piccoli","sequence":"additional","affiliation":[{"name":"Fetal Cardiology Unit Institute of Cardiology  Porto Alegre RS Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Busato","sequence":"additional","affiliation":[{"name":"Fetal Cardiology Unit Institute of Cardiology  Porto Alegre RS Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Klein","sequence":"additional","affiliation":[{"name":"Fetal Cardiology Unit Institute of Cardiology  Porto Alegre RS Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,12,29]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(85)90542-3"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.181.1.1887021"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyg099"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003081-200606000-00006"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2011.30.4.529"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/GRF.0b013e3181fdffd9"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1997.09030148.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2000.00224.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000093195.73667.52"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-2115(03)00123-4"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2013.02.001"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0066-782X2003001400007"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(85)90298-4"},{"key":"e_1_2_5_15_1","first-page":"587","article-title":"Four\u2010quadrant assessment of amniotic fluid volume. 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