{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T10:56:45Z","timestamp":1792061805949,"version":"4.4.0"},"reference-count":22,"publisher":"Wiley","issue":"13","license":[{"start":{"date-parts":[[2015,11,11]],"date-time":"2015-11-11T00:00:00Z","timestamp":1447200000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2015,11,11]],"date-time":"2015-11-11T00:00:00Z","timestamp":1447200000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenat Diagn"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1002\/pd.4706","type":"journal-article","created":{"date-parts":[[2015,10,12]],"date-time":"2015-10-12T22:18:08Z","timestamp":1444688288000},"page":"1353-1357","source":"Crossref","is-referenced-by-count":16,"title":["Challenges in prenatal diagnosis of beta thalassaemia: couples with normal HbA<sub>2<\/sub>\n in one partner"],"prefix":"10.1002","volume":"35","author":[{"given":"Manju","family":"Gorivale","sequence":"first","affiliation":[{"name":"National Institute of Immunohaematology; Indian Council of Medical Research; 13  Floor, New MS Building, KEM Hospital Campus, Parel Mumbai 400012 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pratibha","family":"Sawant","sequence":"additional","affiliation":[{"name":"National Institute of Immunohaematology; Indian Council of Medical Research; 13  Floor, New MS Building, KEM Hospital Campus, Parel Mumbai 400012 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pallavi","family":"Mehta","sequence":"additional","affiliation":[{"name":"National Institute of Immunohaematology; Indian Council of Medical Research; 13  Floor, New MS Building, KEM Hospital Campus, Parel Mumbai 400012 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita","family":"Nadkarni","sequence":"additional","affiliation":[{"name":"National Institute of Immunohaematology; Indian Council of Medical Research; 13  Floor, New MS Building, KEM Hospital Campus, Parel Mumbai 400012 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanjaksha","family":"Ghosh","sequence":"additional","affiliation":[{"name":"National Institute of Immunohaematology; Indian Council of Medical Research; 13  Floor, New MS Building, KEM Hospital Campus, Parel Mumbai 400012 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roshan","family":"Colah","sequence":"additional","affiliation":[{"name":"National Institute of Immunohaematology; Indian Council of Medical Research; 13  Floor, New MS Building, KEM Hospital Campus, Parel Mumbai 400012 India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,11,11]]},"reference":[{"issue":"4","key":"10.1002\/pd.4706-BIB0001|pd4706-cit-0001","first-page":"84","article-title":"Control of thalassaemia in India","volume":"1955","author":"Colah","year":"2014","journal-title":"Thalassaemia Rep"},{"key":"10.1002\/pd.4706-BIB0002|pd4706-cit-0002","first-page":"241","volume-title":"Trends in Haematology","author":"Sukumaran","year":"1975"},{"key":"10.1002\/pd.4706-BIB0003|pd4706-cit-0003","first-page":"1017","article-title":"The burden of haemoglobinopathies in India-time to wake up?","volume":"53","author":"Agarwal","year":"2005","journal-title":"J Assoc Physicians India"},{"issue":"1","key":"10.1002\/pd.4706-BIB0004|pd4706-cit-0004","doi-asserted-by":"crossref","first-page":"16","DOI":"10.4103\/0971-6866.64941","article-title":"Frequency of \u03b2 thalassemia trait and other hemoglobinopathies in northern and western India","volume":"16","author":"Madan","year":"2010","journal-title":"Indian J Hum Genet"},{"key":"10.1002\/pd.4706-BIB0005|pd4706-cit-0005","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1002\/9780470696705.ch4","volume-title":"The Thalassaemia Syndromes","author":"Weatherall","year":"2001","edition":"4"},{"issue":"1","key":"10.1002\/pd.4706-BIB0006|pd4706-cit-0006","first-page":"10","article-title":"Application of covalent reverse dot blot hybridization for rapid prenatal diagnosis of the common Indian thalassemia syndromes","volume":"15","author":"Colah","year":"1997","journal-title":"Ind J Hematol Blood Transfus"},{"key":"10.1002\/pd.4706-BIB0007|pd4706-cit-0007","first-page":"941","volume-title":"Disorders of Hemoglobin: Genetics, Pathophysiology and Clinical Management","author":"Old","year":"2001"},{"key":"10.1002\/pd.4706-BIB0008|pd4706-cit-0008","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1182\/blood.V98.1.250","article-title":"A rapid and reliable 7 deletion multiplex polymerase chain reaction assay for \u03b1-thalassaemia","volume":"98","author":"Tan","year":"2001","journal-title":"Blood"},{"key":"10.1002\/pd.4706-BIB0009|pd4706-cit-0009","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1111\/j.1600-0609.2007.00958.x","article-title":"The clinical significance of the spectrum of interactions of Cap+1(A\u2009\u2192\u2009C), a silent \u03b2-globin gene mutation with other \u03b2 thalassemia mutations and globin gene modifiers in north Indians","volume":"79","author":"Garewal","year":"2007","journal-title":"Eur J Haematol"},{"key":"10.1002\/pd.4706-BIB0010|pd4706-cit-0010","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.bcmd.2008.12.006","article-title":"Regional heterogeneity of beta thalassemia mutations in the multi ethnic Indian population","volume":"42","author":"Colah","year":"2009","journal-title":"Blood Cells Mol Dis"},{"key":"10.1002\/pd.4706-BIB0011|pd4706-cit-0011","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/s11568-010-9132-3","article-title":"Profiling \u03b2-thalassemia mutations in India at state and regional levels: implications for genetic education, screening and counselling programmes","volume":"3","author":"Sinha","year":"2009","journal-title":"Hugo J"},{"issue":"12","key":"10.1002\/pd.4706-BIB0012|pd4706-cit-0012","doi-asserted-by":"crossref","first-page":"2069","DOI":"10.1515\/CCLM.2011.696","article-title":"\u03b2-Thalassemia mutations in subjects with borderline HbA2 values: a pilot study in North India","volume":"49","author":"Rangan","year":"2011","journal-title":"Clin Chem Lab Med"},{"key":"10.1002\/pd.4706-BIB0013|pd4706-cit-0013","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1016\/j.cca.2012.05.019","article-title":"Compromising for carrier detection of beta thalassemia based on measurement of HbA2 levels in unusual cases","volume":"413","author":"Colaco","year":"2012","journal-title":"Clin Chim Acta"},{"issue":"1","key":"10.1002\/pd.4706-BIB0014|pd4706-cit-0014","doi-asserted-by":"crossref","first-page":"24","DOI":"10.3109\/03630269.2013.852568","article-title":"Masking of a \u03b2-thalassemia determinant by a novel \u03b4-globin gene defect [HbA2-Saurashtra or \u03b4100(G2)Pro!Ser; HBD: c.301C4T] in Cis","volume":"38","author":"Colaco","year":"2014","journal-title":"Hemoglobin"},{"issue":"2","key":"10.1002\/pd.4706-BIB0015|pd4706-cit-0015","doi-asserted-by":"crossref","first-page":"114","DOI":"10.3109\/03630269.2011.654144","article-title":"Is the poly A (T\u2009\u2192\u2009C) mutation a causative factor for misdiagnosis in second trimester prenatal diagnosis of \u03b2-thalassaemia by fetal blood analysis on HPLC?","volume":"36","author":"Italia","year":"2012","journal-title":"Hemoglobin"},{"issue":"5","key":"10.1002\/pd.4706-BIB0016|pd4706-cit-0016","doi-asserted-by":"crossref","first-page":"329","DOI":"10.3109\/03630269.2014.951889","article-title":"\u03b2-thalassemia mutations in western India: outcome of prenatal diagnosis in a hemoglobinopathies project","volume":"38","author":"Patel","year":"2014","journal-title":"Hemoglobin"},{"key":"10.1002\/pd.4706-BIB0017|pd4706-cit-0017","doi-asserted-by":"crossref","first-page":"1380","DOI":"10.3324\/haematol.12840","article-title":"Significance of borderline hemoglobin A2 values in an Italian population with a high prevalence of \u03b2-thalassemia","volume":"93","author":"Giambona","year":"2008","journal-title":"Haematologica"},{"issue":"2","key":"10.1002\/pd.4706-BIB0018|pd4706-cit-0018","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.bioelechem.2008.04.010","article-title":"IFCC Working Group on Standardization of HbA2. New analytical tools and epidemiological data for the identification of HbA2 borderline subjects in the screening for beta-thalassemia","volume":"73","author":"Mosca","year":"2008","journal-title":"Bioelectrochemistry"},{"issue":"2","key":"10.1002\/pd.4706-BIB0019|pd4706-cit-0019","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1002\/ajh.2830460204","article-title":"Genotype of subjects with borderline hemoglobin A2levels: implication for beta-thalassemia carrier screening","volume":"46","author":"Galanello","year":"1994","journal-title":"Am J Hematol"},{"issue":"1","key":"10.1002\/pd.4706-BIB0020|pd4706-cit-0020","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/s12288-012-0190-7","article-title":"Prevalence of iron deficiency in thalassemia minor","volume":"30","author":"Madan","year":"2014","journal-title":"Indian J Hematol Blood Transfus"},{"issue":"4","key":"10.1002\/pd.4706-BIB0021|pd4706-cit-0021","doi-asserted-by":"crossref","first-page":"252","DOI":"10.3109\/03630269.2014.913517","article-title":"Interaction of iron deficiency anemia and hemoglobinopathies among college students and pregnant women: a multi centre evaluation in India","volume":"38","author":"Mohanty","year":"2014","journal-title":"Hemoglobin"},{"issue":"2","key":"10.1002\/pd.4706-BIB0022|pd4706-cit-0022","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1080\/1024533050069882","article-title":"Jaundice and alpha gene triplication in beta-thalassemia: association or causation?","volume":"11","author":"Panigrahi","year":"2006","journal-title":"Hematology"}],"container-title":["Prenatal Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.4706","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.4706","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1002\/pd.4706\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,3]],"date-time":"2021-07-03T23:51:39Z","timestamp":1625356299000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pd.4706"}},"subtitle":["Prenatal diagnosis of <i>\u03b2<\/i>\n-thalassaemia in couples with normal HbA<sub>2<\/sub>\n in one partner"],"short-title":[],"issued":{"date-parts":[[2015,11,11]]},"references-count":22,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2015,12]]}},"URL":"https:\/\/doi.org\/10.1002\/pd.4706","archive":["Portico"],"relation":{},"ISSN":["0197-3851"],"issn-type":[{"value":"0197-3851","type":"print"}],"subject":[],"published":{"date-parts":[[2015,11,11]]}}}