{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T10:10:06Z","timestamp":1696587006087},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,12,23]],"date-time":"2015-12-23T00:00:00Z","timestamp":1450828800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Our objective was to describe utilization and impact of sonographic growth assessment in pregnancies with low pregnancy\u2010associated plasma protein\u2010A (PAPP\u2010A).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Singleton pregnancies with PAPP\u2010A \u22645th percentile and no other risk factors for fetal growth restriction from January 2011\u2013June 2013 were included. Antepartum and delivery data were obtained by reviewing medical records. Outcomes of pregnancies referred for sonographic growth assessment were compared with those not referred for ultrasound. Fisher's exact test, chi\u2010square analysis, and Mann\u2013Whitney U were used for statistical comparison.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Two hundred ninety\u2010five patients were included. Of 285 pregnancies reaching the third trimester, 77.5% were referred for ultrasound, with the initial scan at a median gestational age of 28\u2009weeks [26\u201329]. Referral for growth scans was associated with earlier gestational age at delivery and higher rates of delivery for fetal indications. Those who did not undergo growth scans were more likely to deliver a small for gestational age infant at term, 20.7% versus 35.0% (<jats:italic>p<\/jats:italic>\u2009=\u20090.04). There was one third\u2010trimester fetal demise, occurring in a patient who had been undergoing growth scans.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Growth scans in those with low PAPP\u2010A were associated with delivery at earlier gestational age, with higher rates of delivery for fetal indications and lower rates of small for gestational age newborns at term. No significant differences in neonatal outcomes were observed. \u00a9 2015 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.4723","type":"journal-article","created":{"date-parts":[[2015,11,9]],"date-time":"2015-11-09T13:56:40Z","timestamp":1447077400000},"page":"112-116","source":"Crossref","is-referenced-by-count":1,"title":["Low PAPP\u2010A: the impact of ultrasound to evaluate fetal growth"],"prefix":"10.1002","volume":"36","author":[{"given":"Armin S.","family":"Razavi","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Weill Cornell Medical Center  New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen T.","family":"Chasen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Weill Cornell Medical Center  New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,12,23]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.06.052"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000172419.37410.eb"},{"key":"e_1_2_6_4_1","volume-title":"Screening for Fetal Chromosomal Abnormalities","author":"ACOG Committee on Practice Bulletins","year":"2007"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181da93da"},{"key":"e_1_2_6_6_1","volume-title":"Fetal Growth Restriction","author":"ACOG Committee on Practice Bulletins","year":"2013"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2431-3-6"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.6274"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2013.176"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2013.02.012"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1053\/plac.2002.0944"},{"key":"e_1_2_6_12_1","volume-title":"Noninvasive Prenatal Testing for Fetal Aneuploidy","author":"American College of Obstetricians and Gynecologists Committee on Genetics","year":"2012"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1311037"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.12249"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2008.02065.x"}],"container-title":["Prenatal Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.4723","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpd.4723","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pd.4723","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T02:18:58Z","timestamp":1696472338000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/pd.4723"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,23]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["10.1002\/pd.4723"],"URL":"https:\/\/doi.org\/10.1002\/pd.4723","archive":["Portico"],"relation":{},"ISSN":["0197-3851","1097-0223"],"issn-type":[{"value":"0197-3851","type":"print"},{"value":"1097-0223","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12,23]]}}}