{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T04:18:41Z","timestamp":1777695521210,"version":"3.51.4"},"reference-count":22,"publisher":"Wiley","issue":"13","license":[{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the association between ultrasonographic renal parameters and urine biochemistry in fetuses with lower urinary tract obstruction (LUTO).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data were collected prospectively from 31 consecutive fetuses with LUTO that underwent vesicocentesis for fetal urinary biochemistry between April 2013 and September 2015. The following renal ultrasound markers were assessed immediately before the vesicocentesis: renal echogenicity, presence of cortical cysts, presence of findings suggestive of \u2018renal dysplasia\u2019 (hyperechogenic cystic kidneys with no cortical\u2010medullary differentiation) and severe oligohydramnios (amniotic fluid\u2009&lt;\u20095th percentile). The association of these parameters to the fetal urinary concentration of sodium, chloride, calcium, osmolality and beta2\u2010microglobulin was investigated by logistic regression analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was no relationship between any of the ultrasonographic fetal renal characteristics and fetal urinary biochemistry.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In LUTO, the ultrasound appearance of the fetal kidneys and urinary biochemistry are not correlated. It may be better to take both ultrasound and biochemistry into account when evaluating fetuses with fetal LUTO. \u00a9 2016 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.4958","type":"journal-article","created":{"date-parts":[[2016,11,14]],"date-time":"2016-11-14T17:36:40Z","timestamp":1479145000000},"page":"1206-1210","source":"Crossref","is-referenced-by-count":29,"title":["Are ultrasound renal aspects associated with urinary biochemistry in fetuses with lower urinary tract obstruction?"],"prefix":"10.1002","volume":"36","author":[{"given":"Ahmed A.","family":"Nassr","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Baylor College of Medicine and Texas Children's Fetal Center  Houston TX USA"},{"name":"Department of Obstetrics and Gynecology, Women's Health Hospital Assiut University  Asiut Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chester Koh","family":"Koh","sequence":"additional","affiliation":[{"name":"Division of Pediatric Urology Texas Children's Hospital Pavilion for Women  Houston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alireza A.","family":"Shamshirsaz","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Baylor College of Medicine and Texas Children's Fetal Center  Houston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jimmy","family":"Espinoza","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Baylor College of Medicine and Texas Children's Fetal Center  Houston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haleh","family":"Sangi\u2010Haghpeykar","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Baylor College of Medicine and Texas Children's Fetal Center  Houston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dina","family":"Sharhan","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Baylor College of Medicine and Texas Children's Fetal Center  Houston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Welty","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Baylor College of Medicine and Texas Children's Fetal Center, Texas Children's Hospital Pavilion for Women  Houston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Angelo","sequence":"additional","affiliation":[{"name":"Renal Section Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital  Houston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Roth","sequence":"additional","affiliation":[{"name":"Division of Pediatric Urology Texas Children's Hospital Pavilion for 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