{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T18:03:08Z","timestamp":1787508188098,"version":"build-2736575974"},"reference-count":61,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2017,8,7]],"date-time":"2017-08-07T00:00:00Z","timestamp":1502064000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The purpose of this systematic review is to provide a comprehensive overview on the clinical course, perinatal outcome, and effectiveness of prenatal management options for pericardial teratoma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A comprehensive search including Ovid MEDLINE, Ovid EMBASE, and Scopus was conducted from inception to September 2016. All studies that reported the prenatal course of pericardial teratoma in singleton or twin gestations were considered eligible. Standardized forms were used for data abstraction by two independent reviewers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Out of 217 screened abstracts, 59 studies reporting 67 fetuses with pericardial teratoma were included. Twenty\u2010three singleton fetuses and 3 fetuses in twin gestations underwent prenatal treatment, and 20 (76.9%) of them were hydropic at the time of intervention. Of those, 15\/20 (75%) had a favorable outcome. In the non\u2010intervention group (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a041), 26 (63.4%) developed hydrops, and out of those, 8 (30.8%) had a favorable outcome.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Prenatal fluid drainage and other prenatal techniques have been utilized in the treatment of intrapericardial teratoma. While most fetuses tolerated pericardiocentesis, the neonatal benefit of this procedure is still uncertain, and outcomes of other interventions had variable success. Prenatal intervention for pericardial teratoma may be an option in specialized units but, given the maternal and fetal risks, needs careful consideration. \u00a9 2017 John Wiley &amp; Sons, Ltd.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pd.5113","type":"journal-article","created":{"date-parts":[[2017,7,10]],"date-time":"2017-07-10T20:18:45Z","timestamp":1499717925000},"page":"849-863","source":"Crossref","is-referenced-by-count":38,"title":["Prenatal management of fetal intrapericardial teratoma: a systematic review"],"prefix":"10.1002","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1924-7965","authenticated-orcid":false,"given":"Ahmed A.","family":"Nassr","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Baylor College of Medicine and Texas Children's Fetal Center  Houston TX USA"},{"name":"Women's Health Hospital Assiut University  Assiut Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sherif A.","family":"Shazly","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Mayo Clinic College of Medicine  Rochester MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8056-0934","authenticated-orcid":false,"given":"Shaine A.","family":"Morris","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology Baylor College of Medicine and Texas Children's Fetal Center  Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy","family":"Ayres","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology Baylor College of Medicine and Texas Children's Fetal Center  Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jimmy","family":"Espinoza","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Baylor College of Medicine and Texas Children's Fetal Center  Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hadi","family":"Erfani","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Baylor College of Medicine and Texas Children's Fetal Center  Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olutoyin A.","family":"Olutoye","sequence":"additional","affiliation":[{"name":"Division of Pediatric Anesthesia Baylor College of Medicine and Texas Children's Fetal Center  Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara K.","family":"Sexson","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology Baylor College of Medicine and Texas Children's Fetal Center  Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oluyinka O.","family":"Olutoye","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery Baylor College of Medicine and Texas Children's Fetal Center  Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Charles D.","family":"Fraser","sequence":"additional","affiliation":[{"name":"Division of Congenital Heart Surgery Baylor College of Medicine and Texas Children's Heart Center  Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael A.","family":"Belfort","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Baylor College of Medicine and Texas Children's Fetal Center  Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6333-3177","authenticated-orcid":false,"given":"Alireza A.","family":"Shamshirsaz","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Baylor College of Medicine and Texas Children's Fetal Center  Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,8,7]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"286","article-title":"Neoplasms of the fetus and neonate","volume":"22","author":"Dehner L","year":"1981","journal-title":"Monogr Pathol"},{"key":"e_1_2_5_3_1","unstructured":"Gonzalez\u2010CrussiF.Extragonadal teratomas: Armed Forces Institute of Pathology 1982:95\u201399."},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000146006.46468.ef"},{"key":"e_1_2_5_5_1","first-page":"1","volume-title":"Tumors of the Cardiovascular System. 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