{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T07:26:52Z","timestamp":1780730812397,"version":"3.54.1"},"reference-count":27,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,1,9]],"date-time":"2018-01-09T00:00:00Z","timestamp":1515456000000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare outcomes between 2 umbilical cord occlusion (UCO) methods: radiofrequency ablation (RFA) versus fetoscopic\u2010guided laser photocoagulation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective study of all monochorionic diamniotic multiple gestations that underwent UCO with RFA (preferred after 2014) or laser (preferred before 2014). In bivariate analysis, patients treated with RFA were compared with laser. Risk factors for intrauterine fetal demise (IUFD) and 30\u2010day survival of the co\u2010twin were identified, and multiple logistic models were fitted to examine whether the UCO method was associated with these outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 60 UCO cases, 18 (30%) underwent RFA and 42 (70%) underwent laser surgery. The RFA method was associated with co\u2010twin IUFD after surgery (6\/18 [33.3%] vs 1\/42 [2.4%], <jats:italic>P<\/jats:italic>\u00a0=\u00a00.0021). In logistic regression models, patients who underwent RFA were <jats:italic>more<\/jats:italic> likely than patients who underwent laser to have an IUFD of the co\u2010twin (OR 13.2, 1.23\u2013142.62, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.0331). These patients were also <jats:italic>less<\/jats:italic> likely to have 30\u2010day survival of the co\u2010twin, although this was not statistically significant (OR 0.20, 0.04\u20131.15, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.0710).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Despite clear technical advantages of RFA compared with laser, we found that RFA appeared to be associated with increased risk of post\u2010procedure fetal demise. Further studies should be conducted to confirm these findings.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.5196","type":"journal-article","created":{"date-parts":[[2017,12,14]],"date-time":"2017-12-14T13:16:36Z","timestamp":1513257396000},"page":"110-116","source":"Crossref","is-referenced-by-count":24,"title":["Comparison of umbilical cord occlusion methods: Radiofrequency ablation versus laser photocoagulation"],"prefix":"10.1002","volume":"38","author":[{"given":"Mira","family":"Abdel\u2010Sattar","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Division of Maternal\u2010Fetal Medicine, Keck School of Medicine University of Southern California  Pasadena CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew H.","family":"Chon","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Division of Maternal\u2010Fetal Medicine, Keck School of Medicine University of Southern California  Pasadena CA 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