{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T05:44:48Z","timestamp":1780983888391,"version":"3.54.1"},"reference-count":16,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,3,8]],"date-time":"2018-03-08T00:00:00Z","timestamp":1520467200000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Building up Diagnosis and Treatment Center of Congenital Heart Disease","award":["GWIV-23"],"award-info":[{"award-number":["GWIV-23"]}]},{"name":"Promoting the prenatal screening and perinatal intervention of congenital heart disease with the help of STIC","award":["SHDC12015102"],"award-info":[{"award-number":["SHDC12015102"]}]},{"name":"Value of STIC technology in diagnosing fetal congenital heart diseases","award":["16CR2021A"],"award-info":[{"award-number":["16CR2021A"]}]},{"name":"Indentifying congenital heart disease automatically with the help of computer","award":["YG2015MS70"],"award-info":[{"award-number":["YG2015MS70"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To compare the fetal echocardiographic measurements and neonatal outcome of fetuses with diagnosis of critical pulmonary stenosis (CPS\/IVS) and pulmonary atresia with intact ventricular septum (PA\/IVS) to identify the predictors of neonatal ductus dependence and the need for neonatal intervention.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Forty\u2010four fetuses with a diagnosis of membranous PA\/IVS or CPS\/IVS referred to Shanghai Xinhua Hospital Affiliated to Shanghai Jiaotong University between June 2009 and November 2014 were respectively analyzed. We analyzed their fetal and pediatric echocardiographic features and clinical features after birth.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the 29 infants in the final analysis, 19 were ductal dependent and were diagnosed as CPS\/IVS or PA\/IVS after birth. Ten patients with fetal CSP\/IVS were ductal independent and were diagnosed as pulmonary stenosis after birth. In midtrimester, significance was only detected in pulmonary valve (PV) regurgitation between 2 groups (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.009). The fetuses with PV regurgitation in midtrimester were more likely to be ductal independent (odds ratio\u00a0=\u00a06.67; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.010) than those with absence of PV regurgitation in the midtrimester scan. In late trimester, the infants in ductus\u2010independent group had better fetal right ventricular development than those in ductus dependent group. The right ventricle over left ventricle length ratio in last scan over 0.86 had the best capability in predicting ductus independence during neonatal period with help of receiver\u2010operating characteristic curve and the logistic regression analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Among fetuses with pulmonary valve stenosis and right ventricle dysplasia at the time of first fetal echo in midtrimester, use of pulmonary valve regurgitation can identify who will be ductal dependent at births. In late trimester, right ventricle over left ventricle length ratio less than 0.86 had the best capability of predicting neonatal ductal dependence. Fetuses with reversed ductus arteriosus flow direction in late trimester were more likely to be ductus dependent after birth.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.5224","type":"journal-article","created":{"date-parts":[[2018,2,8]],"date-time":"2018-02-08T02:32:43Z","timestamp":1518057163000},"page":"273-279","source":"Crossref","is-referenced-by-count":4,"title":["Fetal pulmonary valve stenosis or atresia with intact ventricular septum: Predictors of need for neonatal intervention"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9690-4079","authenticated-orcid":false,"given":"Qing","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Pediatric Cardiology, Xinhua Hospital, School of Medicine Shanghai Jiaotong University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu Rong","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology, Xinhua Hospital, School of Medicine Shanghai Jiaotong University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xian Ting","family":"Jiao","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology, Xinhua Hospital, School of Medicine Shanghai Jiaotong University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng Fei","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology, Xinhua Hospital, School of Medicine Shanghai Jiaotong University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li Qing","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology, Xinhua Hospital, School of Medicine Shanghai Jiaotong University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sun","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology, Xinhua Hospital, School of Medicine Shanghai Jiaotong University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology, Xinhua Hospital, School of Medicine Shanghai Jiaotong University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,3,8]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"369","article-title":"Percutaneous balloon valvuloplasty for the treatment of pulmonary valve stenosis in children\u2014a single centre experience","volume":"67","author":"Wery\u0144ski P","year":"2009","journal-title":"Kardiol Pol"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(61)90366-0"},{"key":"e_1_2_10_4_1","first-page":"69","article-title":"Determinants of outcome in fetal pulmonary valve stenosis or atresia with intact ventricular septum","volume":"99","author":"Roman KS","year":"2008","journal-title":"Am J Cardiol"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.150.2.6691115"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2004.04.011"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(92)90300-N"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.2597"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.81.6.661"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1159\/000357429"},{"issue":"26","key":"e_1_2_10_11_1","first-page":"1","article-title":"Prenatal detection of congenital heart disease","volume":"155","author":"Friedberg MK","year":"2009","journal-title":"J 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