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Two other stillbirth cousins presented with fetal hydrops and congenital hemochromatosis' phenotype at 37 and 12\u00a0weeks of gestation. Molecular screening revealed the presence of a c.613G&gt;A pathogenic allelic variation in exon 4 of<jats:italic>GATA1<\/jats:italic>gene in the 3 male siblings and their carrier mothers.<\/jats:p><jats:p>The diagnosis of a<jats:italic>GATA1<\/jats:italic>gene mutation may be suspected in cases of male fetuses with intracerebral bleeding, particularly if a history of prior fetal loss(es) and mild maternal thrombocytopenia are also present.<\/jats:p>","DOI":"10.1002\/pd.5320","type":"journal-article","created":{"date-parts":[[2018,6,27]],"date-time":"2018-06-27T14:40:39Z","timestamp":1530110439000},"page":"772-778","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Fetal cerebral hemorrhage due to X\u2010linked<i>GATA1<\/i>gene mutation"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8482-2815","authenticated-orcid":false,"given":"Hanane","family":"Bouchghoul","sequence":"first","affiliation":[{"name":"Department of Gynecology and Obstetrics Kremlin\u2010Bic\u00eatre Hospital Kremlin\u2010Bic\u00eatre France"},{"name":"University Paris\u2010Sud Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chlo\u00e9","family":"Quelin","sequence":"additional","affiliation":[{"name":"Department of Genetics Sud Hospital Rennes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Loget","sequence":"additional","affiliation":[{"name":"Department of Anatomo\u2010Pathology Pontchaillou Hospital Rennes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F\u00e9r\u00e9cht\u00e9","family":"Encha\u2010Razavi","sequence":"additional","affiliation":[{"name":"Unit of Fetal Pathology Antoine B\u00e9cl\u00e8re Hospital Clamart France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie\u2010Victoire","family":"Senat","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics Kremlin\u2010Bic\u00eatre Hospital Kremlin\u2010Bic\u00eatre France"},{"name":"University Paris\u2010Sud Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorraine","family":"Maheut","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics Mutualiste la Sagesse Clinic Rennes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Galimand","sequence":"additional","affiliation":[{"name":"Hematology Diagnosis Laboratory Robert Debr\u00e9 Hospital Paris France"},{"name":"University Paris7\u2010Denis Diderot Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Collardeau\u2010Frachon","sequence":"additional","affiliation":[{"name":"Department of Pathology Femme\u2010Mere\u2010Enfant Hospital Bron France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lydie","family":"Da Costa","sequence":"additional","affiliation":[{"name":"Hematology Diagnosis Laboratory Robert Debr\u00e9 Hospital Paris France"},{"name":"University Paris7\u2010Denis Diderot Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4595-7271","authenticated-orcid":false,"given":"Jelena","family":"Martinovic","sequence":"additional","affiliation":[{"name":"Unit of Fetal Pathology Antoine B\u00e9cl\u00e8re Hospital Clamart France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,7,24]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1969"},{"issue":"6","key":"e_1_2_8_3_1","doi-asserted-by":"crossref","first-page":"789","DOI":"10.47102\/annals-acadmedsg.WongJPL","article-title":"Characteristics of six newborn infants with postnatal findings of severe intracranial haemorrhage","volume":"33","author":"Wong JP","year":"2004","journal-title":"Ann Acad Med Singapore"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2007.01469.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.11070"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.12268"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2013.135"},{"key":"e_1_2_8_8_1","first-page":"668","article-title":"The major human erythroid DNA\u2010binding protein (GF\u20101): Primary sequence and localization of the gene to the X chromosome","volume":"87","author":"Zon LI","year":"1990","journal-title":"Biochemistry"},{"key":"e_1_2_8_9_1","unstructured":"Genetics home reference. 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