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We describe a case of monosomy X\u2010positive noninvasive prenatal testing that was discordant with the 46,XX results from amniocentesis and postnatal testing. This monosomy X pregnancy doubled the single X chromosome, leading to 45,X\/46,XX mosaicism in the placenta and uniparental isodisomy X in the amniotic fluid. Thus, at least some discordant monosomy X results are due to true mosaicism in the pregnancy, which has important implications for clinical outcome and patient counseling.<\/jats:p>","DOI":"10.1002\/pd.5349","type":"journal-article","created":{"date-parts":[[2018,8,30]],"date-time":"2018-08-30T07:45:51Z","timestamp":1535615151000},"page":"920-923","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Monosomy X rescue explains discordant NIPT results and leads to uniparental isodisomy"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6233-2316","authenticated-orcid":false,"given":"M. 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