{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T04:58:47Z","timestamp":1776401927837,"version":"3.51.2"},"reference-count":31,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2019,5,20]],"date-time":"2019-05-20T00:00:00Z","timestamp":1558310400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:p>What is already known about this topic?\n<jats:list list-type=\"bullet\">\n<jats:list-item><jats:p>Fetal aortic valvuloplasty may prevent progression to hypoplastic left heart syndrome (HLHS) in utero and, thus, decrease postnatal morbidity<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Despite the high survival rate of HLHS in developed countries, many studies suggest that the risks of this fetal intervention may outweigh the benefits.<\/jats:p><\/jats:list-item>\n<\/jats:list><\/jats:p><jats:p>What does this study add?\n<jats:list list-type=\"bullet\">\n<jats:list-item><jats:p>Fetal aortic valvuloplasty is associated with \u224850% long\u2010term survival, while HLHS currently carries more than 95% risk of perinatal death in countries with suboptimal postnatal management, with little or no experience regarding surgical palliation, and with the vast majority of cases receiving comfort measures.<\/jats:p><\/jats:list-item>\n<\/jats:list><\/jats:p>","DOI":"10.1002\/pd.5470","type":"journal-article","created":{"date-parts":[[2019,5,2]],"date-time":"2019-05-02T17:45:43Z","timestamp":1556819143000},"page":"563-570","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Outcomes of hypoplastic left heart syndrome and fetal aortic valvuloplasty in 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