{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T12:03:20Z","timestamp":1790942600895,"version":"4.1.0"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2003,2,3]],"date-time":"2003-02-03T00:00:00Z","timestamp":1044230400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2003,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Primary ciliary dyskinesia (PCD), also referred to as immotile\u2010cilia syndrome or Kartagener syndrome, is a group of genetic disorders caused by defective cilia leading to chronic sinupulmonary infection, situs inversus and reduced fertility. Some PCD patients also have cerebral ventriculomegaly or hydrocephalus.<\/jats:p><jats:p>We report here two fetuses and one newborn with mild cerebral ventriculomegaly and a suspected and\/or confirmed diagnosis of PCD. These cases demonstrate that mild fetal cerebral ventriculomegaly can be a prenatal sonographic marker of PCD, certainly in fetuses with situs inversus or a history of a previous sib with PCD. Copyright \u00a9 2003 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/pd.551","type":"journal-article","created":{"date-parts":[[2003,3,18]],"date-time":"2003-03-18T16:10:50Z","timestamp":1048003850000},"page":"239-242","source":"Crossref","is-referenced-by-count":45,"title":["Mild fetal cerebral ventriculomegaly as a prenatal sonographic marker for Kartagener syndrome"],"prefix":"10.1002","volume":"23","author":[{"given":"Marja W.","family":"Wessels","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolette S.","family":"den Hollander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick J.","family":"Willems","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2003,2,3]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1084576"},{"key":"e_1_2_1_3_1","first-page":"4817","volume-title":"The Metabolic and Genetic Bases of Inherited Disease","author":"Afzelius BA","year":"2001"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(97)00112-9"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(91)90530-5"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/1096-8628(20010715)101:4<339::AID-AJMG1442>3.0.CO;2-P"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00612944"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI4786"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000111291"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.65.5.543"},{"key":"e_1_2_1_11_1","doi-asserted-by":"crossref","first-page":"439","DOI":"10.2460\/ajvr.1990.51.03.439","article-title":"Suspected ciliary dysfunction in Chinese Shar Pei pups with pneumonia","volume":"51","author":"Dhein CR","year":"1990","journal-title":"Am J Vet Res"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320330303"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.59.5.481"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1086\/319511"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.2174\/1566524023363031"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/11.6.715"},{"key":"e_1_2_1_17_1","first-page":"468","article-title":"Hydrocephalus in Kartagener's syndrome","volume":"65","author":"Jabourian Z","year":"1986","journal-title":"Ear Nose Throat J"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.138"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01954280"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.88"},{"key":"e_1_2_1_21_1","first-page":"607","article-title":"Situs inversus and long\u2010term bronchopneumopathies, existing since the neonatal period","volume":"35","author":"Monnet P","year":"1978","journal-title":"Arch Fr Pediatr"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00305310"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)81705-5"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng817"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1086\/302683"},{"issue":"1","key":"e_1_2_1_26_1","first-page":"20","article-title":"Immotile cilia syndrome associated with hydrocephalus and precocious puberty: a case report","volume":"3","author":"Picco P","year":"1993","journal-title":"Eur J Pediatr Surg"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1999.14050320.x"},{"key":"e_1_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00316558"},{"key":"e_1_2_1_29_1","first-page":"341","article-title":"Ultrastructure of respiratory cilia of WIC\u2010Hyd male rats. 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