{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T17:17:33Z","timestamp":1758475053564,"version":"3.40.5"},"reference-count":22,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2019,9,10]],"date-time":"2019-09-10T00:00:00Z","timestamp":1568073600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>We aimed to evaluate the incidence of gastro\u2010intestinal (GI) anomalies and surgical outcome in fetuses diagnosed with either echogenic bowel (EB) or EB plus bowel dilatation (BD) but no associated chromosomal, DNA and\/or additional structural defects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A 10\u2010year (2008\u20102018) retrospective review was performed on all fetuses diagnosed with EB and EB+BD (RES\u201018\u20100000\u2010072Q). Results are reported as number of cases (%) and mean \u00b1SD. Fisher's exact test, Mann\u2010Whitney U test and logistic regression were used to identify differences between groups and predisposing factors for gastro\u2010intestinal anomalies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We identified 41 fetuses with EB and 14 fetuses with EB+BD. Post\u2010natal surgical intervention was required in no patient of the EB group and in 7\/14 (50%) of the EB+BD group, p&lt;0.001. The risk of having a GI anomaly was higher in the EB+BD group (RR 42.0 [2.5\u2010691.6]; p=0.009). Advanced maternal age (p=0.04), ascites (p=0.006) and polyhydramnios (p=0.007) were associated with a higher incidence of GI pathology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In fetuses with no associated chromosomal, DNA and\/or additional structural defects, the finding of EB+BD is associated with 50% incidence of GI anomalies at birth. Advanced maternal age, ascites and polyhydramnios are also associated with higher incidence of GI pathology at birth.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.5552","type":"journal-article","created":{"date-parts":[[2019,8,28]],"date-time":"2019-08-28T22:40:21Z","timestamp":1567032021000},"page":"1115-1119","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Incidence of gastro\u2010intestinal anomalies and surgical outcome of fetuses diagnosed with echogenic bowel and bowel dilatation"],"prefix":"10.1002","volume":"39","author":[{"given":"Ashleigh","family":"Laird","sequence":"first","affiliation":[{"name":"School of Clinical Sciences at Monash Health, Medicine, Nursing and Health Sciences Monash University  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Shekleton","sequence":"additional","affiliation":[{"name":"Fetal Diagnostic Unit, Monash Health  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramesh M.","family":"Nataraja","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery Monash Children's Hospital  Melbourne Victoria Australia"},{"name":"Department of Paediatrics"},{"name":"Department of Surgery,School of Clinical Sciences at Monash Health, Medicine, Nursing and Health Sciences Monash University,  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Kimber","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery Monash Children's Hospital  Melbourne Victoria Australia"},{"name":"Department of Paediatrics"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1259-4304","authenticated-orcid":false,"given":"Maurizio","family":"Pacilli","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery Monash 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