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Fetal characteristics included second and third trimester estimated fetal weight and sex determined by ultrasound. Placental characteristics included first and second trimester placental growth factor concentrations and second and third trimester uterine artery resistance indices.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Maternal characteristics provided the best screening result for gestational hypertension (area\u2010under\u2010the\u2010curve [AUC] 0.79 [95% Confidence interval {CI} 0.76\u20100.81]) with 40% sensitivity at 90% specificity. For preeclampsia, the maternal characteristics model led to a screening performance of AUC 0.74 (95% CI 0.70\u20100.78) with 33% sensitivity at 90% specificity. Addition of second and third trimester placental ultrasound characteristics only improved screening performance for preeclampsia (AUC 0.78 [95% CI 0.75\u20100.82], with 48% sensitivity at 90% specificity).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Routinely measured maternal characteristics, known at the start of pregnancy, can be used in screening for pregnancies at risk of gestational hypertension or preeclampsia within a low\u2010risk multi\u2010ethnic population. Addition of combined second and third trimester placental ultrasound characteristics only improved screening for preeclampsia.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.5683","type":"journal-article","created":{"date-parts":[[2020,3,17]],"date-time":"2020-03-17T11:54:15Z","timestamp":1584446055000},"page":"746-757","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Population screening for gestational hypertensive disorders using maternal, fetal and placental characteristics: A population\u2010based prospective cohort study"],"prefix":"10.1002","volume":"40","author":[{"given":"Jan S.","family":"Erkamp","sequence":"first","affiliation":[{"name":"The Generation R Study Group, Erasmus MC University Medical Center Rotterdam  Rotterdam The Netherlands"},{"name":"Department of Paediatrics, Erasmus MC University Medical Center Rotterdam  Rotterdam The 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