{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T22:45:35Z","timestamp":1774478735620,"version":"3.50.1"},"reference-count":45,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,5,8]],"date-time":"2020-05-08T00:00:00Z","timestamp":1588896000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2020,7]]},"abstract":"Abstract<\/jats:title>Objectives<\/jats:title>The objective of this study was to assess whether the laterality of congenital diaphragmatic hernia (CDH) was a prognostic factor for neonatal survival.<\/jats:p><\/jats:sec>Methods<\/jats:title>This was a cohort study using the French national database of the Reference Center for Diaphragmatic Hernias. The principal endpoint was survival after hospitalization in intensive care.<\/jats:p>We made a comparative study between right CDH and left CDH by univariate and multivariate analysis. Terminations and stillbirths were excluded from analyses of neonatal outcomes.<\/jats:p><\/jats:sec>Results<\/jats:title>A total of 506 CDH were included with 67 (13%) right CDH and 439 left CDH (87%). Rate of survival was 49% for right CDH and 74% for left CDH (P<\/jats:italic> <\u2009.01). Multivariate analysis showed two factors significantly associated with mortality: thoracic herniation of liver (OR 2.27; IC 95% [1.07\u20104.76]; P<\/jats:italic> = .03) and lung\u2010to\u2010head\u2010ratio over under expected (OR 2.99; IC 95% [1.41\u20106.36]; P<\/jats:italic> <\u2009.01). Side of CDH was not significantly associated with mortality (OR 1.87; IC 95% [0.61\u20105.51], P<\/jats:italic> =\u2009.26).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Rate of right CDH mortality is more important than left CDH. Nevertheless after adjusting for lung\u2010to\u2010head\u2010ratio and thoracic herniation of liver, right CDH does not have a higher risk of mortality than left CDH.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.5706","type":"journal-article","created":{"date-parts":[[2020,4,12]],"date-time":"2020-04-12T08:34:05Z","timestamp":1586680445000},"page":"949-957","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Is laterality of congenital diaphragmatic hernia a reliable prognostic factor? 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