{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T21:00:16Z","timestamp":1783112416854,"version":"3.54.6"},"reference-count":68,"publisher":"Wiley","issue":"13","license":[{"start":{"date-parts":[[2020,9,30]],"date-time":"2020-09-30T00:00:00Z","timestamp":1601424000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001782","name":"University of Melbourne","doi-asserted-by":"publisher","award":["Faculty of Medicine Dentistry Health Sciences"],"award-info":[{"award-number":["Faculty of Medicine Dentistry Health Sciences"]}],"id":[{"id":"10.13039\/501100001782","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Parvovirus B19 (B19V) infection is well known for its mild, self\u2010limiting clinical presentations in children, such as erythema infectiosum. Approximately 40% of women of childbearing age are susceptible to B19V infection. While maternal B19V infection usually has a good prognosis<jats:italic>,<\/jats:italic> B19V can cause severe fetal anaemia and pregnancy loss due to its ability to suppress erythroid progenitor cells. Non\u2010invasive ultrasound monitoring for fetal anaemia is usually performed if maternal seroconversion occurs in the first 20\u2009weeks of gestation, with amniocentesis for fetal infection reserved for those who first present with fetal anaemia or hydrops of unknown cause. Intrauterine transfusion is the standard treatment for severe fetal anaemia and is associated with a significant improvement in survival. However, survivors of hydrops fetalis may have a higher rate of long\u2010term neurodevelopmental complications compared with non\u2010hydropic survivors. This review aims to synthesise published data on the diagnosis, surveillance and outcomes of congenital parvovirus infection to assist clinicians in diagnosing and managing this important condition.<\/jats:p>","DOI":"10.1002\/pd.5819","type":"journal-article","created":{"date-parts":[[2020,8,29]],"date-time":"2020-08-29T09:33:55Z","timestamp":1598693635000},"page":"1722-1731","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Identification and management of congenital parvovirus <scp>B19<\/scp> infection"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0447-7917","authenticated-orcid":false,"given":"Lucy O.","family":"Attwood","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases Austin Health  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8501-4054","authenticated-orcid":false,"given":"Natasha E.","family":"Holmes","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Austin Health  Melbourne Victoria Australia"},{"name":"Department of Perinatal Medicine Mercy Hospital for Women  Melbourne Victoria Australia"},{"name":"Department of Medicine and Radiology The University of Melbourne  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9720-3562","authenticated-orcid":false,"given":"Lisa","family":"Hui","sequence":"additional","affiliation":[{"name":"Department of Perinatal Medicine Mercy Hospital for Women  Melbourne Victoria Australia"},{"name":"Department of Obstetrics and Gynaecology The University of Melbourne  Melbourne Victoria Australia"},{"name":"Reproductive Epidemiology group Murdoch Children's Research Institute  Parkville Victoria Australia"},{"name":"Department of Obstetrics and Gynaecology Northern Health  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,9,30]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.19092"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.15.3.485-505.2002"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.2714"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199404283301704"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.2006.01697.x"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2007.08.005"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/GCO.0b013e3283505a9d"},{"key":"e_1_2_10_9_1","unstructured":"Parvovirus.2014. In: Management of Perinatal Infections [Internet]. Sydney: Australian Society for Infectious Diseases (ASID); [51\u20135].https:\/\/www.asid.net.au\/documents\/item\/368."},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000466430.19823.53"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1701-2163(15)30390-X"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0268-960X(95)90023-3"},{"key":"e_1_2_10_13_1","first-page":"69","article-title":"Parvovirus B19 infection and its significance in pregnancy","volume":"24","author":"Gilbert GL","year":"2000","journal-title":"Commun Dis Intell"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268807009661"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2010.07.014"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00854-11"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2009.02109.x"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.3930"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-01-0069"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.548156"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000155615.68924.B3"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.110.958249"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2014-308080"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1053\/plac.1998.0353"},{"key":"e_1_2_10_25_1","unstructured":"Micha\u0142Komorniczak(Poland) released under Creative Commons 3.0. Attribution\u2010ShareAlike (CC BY\u2010SA 3.0)licence based on: B.F. Rodak G.A. Fritsma. K. Doig: Hematology: Clinical Principles and Applications. 3rd ed. Saunder 2007."},{"key":"e_1_2_10_26_1","volume-title":"Hematology: Basic Principles and Practice","author":"Hoffman R","year":"2009"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.940"},{"issue":"4","key":"e_1_2_10_28_1","first-page":"63","article-title":"Parvovirus B19 during pregnancy: a review","volume":"4","author":"Giorgio E","year":"2010","journal-title":"J Prenat Med"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200001063420102"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.12371"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0960-7692.2001.00540.x"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2002.128024"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.23588"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2015.09.006"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1159\/000020914"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1159\/000020794"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0223(199806)18:6<599::AID-PD313>3.0.CO;2-P"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.8904"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/cga.12156"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1168"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.3109\/15513819309048224"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.3109\/15513819509026944"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-010-9803-9"},{"issue":"11","key":"e_1_2_10_44_1","first-page":"995","article-title":"Investigation of parvovirus B19 in cardiac tissue from patients with congenital heart disease","volume":"112","author":"Wang X","year":"1999","journal-title":"Chin Med J (Engl)"},{"key":"e_1_2_10_45_1","first-page":"463571","article-title":"A case of fetal parvovirus b19 myocarditis that caused terminal heart failure","volume":"2014","author":"Hichijo A","year":"2014","journal-title":"Case Rep Obstet Gynecol"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1159\/000053953"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2007.01555.x"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1159\/000236149"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2006.08.041"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.5674"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2001.00471.x"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.20273"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.3925"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.1159\/000477208"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kws177"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2019.03.004"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(98)70203-0"},{"key":"e_1_2_10_58_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1998.tb10048.x"},{"key":"e_1_2_10_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0163-4453(98)90346-2"},{"key":"e_1_2_10_60_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1992.tb13822.x"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2013.04.006"},{"key":"e_1_2_10_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)04647-X"},{"key":"e_1_2_10_63_1","doi-asserted-by":"publisher","DOI":"10.1086\/342575"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.1159\/000180119"},{"key":"e_1_2_10_65_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0031-1285984"},{"key":"e_1_2_10_66_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.4152"},{"key":"e_1_2_10_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2011.12.035"},{"key":"e_1_2_10_68_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000249611.67873.94"},{"key":"e_1_2_10_69_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.12063"}],"container-title":["Prenatal Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pd.5819","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/pd.5819","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pd.5819","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T04:50:02Z","timestamp":1693284602000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/pd.5819"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,30]]},"references-count":68,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["10.1002\/pd.5819"],"URL":"https:\/\/doi.org\/10.1002\/pd.5819","archive":["Portico"],"relation":{},"ISSN":["0197-3851","1097-0223"],"issn-type":[{"value":"0197-3851","type":"print"},{"value":"1097-0223","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,30]]},"assertion":[{"value":"2020-05-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}