{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T13:39:50Z","timestamp":1783345190797,"version":"3.54.6"},"reference-count":17,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2021,10,17]],"date-time":"2021-10-17T00:00:00Z","timestamp":1634428800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate laparoscopy\u2010assisted fetoscopic laser photocoagulation (FLPC) of placental anastomoses in the treatment of twin\u2010to\u2010twin\u2010transfusion syndrome (TTTS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>We performed a retrospective cohort study analyzing pregnancies complicated by TTTS who underwent FLPC in a single university\u2010affiliated tertiary medical\u2010center. Outcomes were compared between patients who received laparoscopy\u2010assisted FLPC (study group) and patients who underwent the conventional FLPC technique (control group). Baseline characteristics, sonographic findings, procedure details, and neonatal outcomes were compared between groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The cohort included 278 women with 31 in the study group and 247 in the control group. Sonographic parameters, including fetal biometry and TTTS stage, were comparable between study groups. Gestational age at delivery did not differ between the groups (29.22\u00a0\u00b1\u00a04.55 weeks in the study group vs. 30.62\u00a0\u00b1\u00a04.3 weeks in the control group, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.09). There were no differences in neonatal survival rates at birth and at 30 days between both groups. A subanalysis comparing the laparoscopy\u2010assisted group to only those patients with anterior placenta in the control group, showed a lower rate of incomplete Solomonization in the laparoscopy\u2010assisted study group (3.4% vs. 33%, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Laparoscopy\u2010assisted FLPC is a reasonable and safe option that may be offered in cases of FLPC where an anterior placenta restricts adequate surgical access.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.5955","type":"journal-article","created":{"date-parts":[[2021,10,20]],"date-time":"2021-10-20T09:17:47Z","timestamp":1634721467000},"page":"1582-1588","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Outcomes of laparoscopy\u2010assisted fetoscopic laser photocoagulation for twin\u2013twin transfusion syndrome: An established alternative for inaccessible anterior placenta"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5859-9528","authenticated-orcid":false,"given":"Eyal","family":"Krispin","sequence":"first","affiliation":[{"name":"Division of Fetal Therapy and Surgery Department of Obstetrics and Gynecology Baylor College of Medicine and Texas Children\u2019s Fetal Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6333-3177","authenticated-orcid":false,"given":"Ahmed A.","family":"Nassr","sequence":"additional","affiliation":[{"name":"Division of Fetal Therapy and Surgery Department of Obstetrics and Gynecology Baylor College of Medicine and Texas Children\u2019s Fetal Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9830-2212","authenticated-orcid":false,"given":"Jimmy","family":"Espinoza","sequence":"additional","affiliation":[{"name":"Division of Fetal Therapy and Surgery Department of Obstetrics and Gynecology Baylor College of Medicine and Texas Children\u2019s Fetal Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roopali","family":"Donepudi","sequence":"additional","affiliation":[{"name":"Division of Fetal Therapy and Surgery Department of Obstetrics and Gynecology Baylor College of Medicine and Texas Children\u2019s Fetal Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raphael C.","family":"Sun","sequence":"additional","affiliation":[{"name":"Division of Fetal Therapy and Surgery Department of Obstetrics and Gynecology Baylor College of Medicine and Texas Children\u2019s Fetal Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0265-9859","authenticated-orcid":false,"given":"Magda","family":"Sanz\u2010Cortes","sequence":"additional","affiliation":[{"name":"Division of Fetal Therapy and Surgery Department of Obstetrics and Gynecology Baylor College of Medicine and Texas Children\u2019s Fetal Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shayan","family":"Mostafaei","sequence":"additional","affiliation":[{"name":"Department of Biostatistics School of Health Kermanshah University of Medical Sciences  Kermanshah Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael A.","family":"Belfort","sequence":"additional","affiliation":[{"name":"Division of Fetal Therapy and Surgery Department of Obstetrics and Gynecology Baylor College of Medicine and Texas Children\u2019s Fetal Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alireza A.","family":"Shamshirsaz","sequence":"additional","affiliation":[{"name":"Division of Fetal Therapy and Surgery Department of Obstetrics and Gynecology Baylor College of Medicine and Texas Children\u2019s Fetal Center  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