{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T04:02:42Z","timestamp":1792555362204,"version":"4.5.0"},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,6,16]],"date-time":"2021-06-16T00:00:00Z","timestamp":1623801600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess the effect of Fetal Endoscopic Tracheal Occlusion (FETO) on neonatal survival in fetuses with left congenital diaphragmatic hernia (CDH) and moderate lung hypoplasia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>CDH fetuses with moderate pulmonary hypoplasia (observed\/expected lung area to head ratio between 26% and 35%, or between 36% and 45% with liver herniation) were prospectively recruited. Included patients were matched to a control group who were ineligible for FETO. Primary outcomes were survival at 28\u00a0days, at discharge, and at 6\u00a0months of age, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>58 cases were recruited, 29 treated with FETO and 29 matched controls. Median gestational age (GA) at balloon placement and removal were 29.6 and 33.6\u00a0weeks, respectively. FETO group showed significantly lower GA at delivery (35.2 vs. 37.1\u00a0weeks, respectively, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.01), higher survival at 28\u00a0days (51.7 vs. 24.1%, respectively, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.03), at discharge (48.3 vs. 24.1%, respectively, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.06), and at six months of age (41.4 vs. 24.1%, respectively, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.16), and significantly lower length of ventilatory support (17.8 vs. 32.3\u00a0days, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.01) and NICU stay (34.2 vs. 58.3\u00a0days, <jats:italic>p\u00a0<\/jats:italic>=\u00a0&lt;0.01) compared to controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>FETO was associated with a non\u2010significant increase in survival and significantly lower neonatal respiratory morbidity among CDH fetuses with moderate lung hypoplasia.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.5988","type":"journal-article","created":{"date-parts":[[2021,6,15]],"date-time":"2021-06-15T10:19:15Z","timestamp":1623752355000},"page":"310-317","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Impact of fetal endoscopic tracheal occlusion in fetuses with congenital diaphragmatic hernia and moderate lung hypoplasia"],"prefix":"10.1002","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5999-866X","authenticated-orcid":false,"given":"Rogelio","family":"Cruz\u2010Mart\u00ednez","sequence":"first","affiliation":[{"name":"Fetal Medicine and Surgery Center Medicina Fetal M\u00e9xico, and Fetal Medicine Mexico Foundation  Queretaro Mexico"},{"name":"Instituto de Ciencias en Salud (ICSA) Universidad Aut\u00f3noma del Estado de Hidalgo (UAEH)  Hidalgo 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Center Medicina Fetal M\u00e9xico, and Fetal Medicine Mexico Foundation  Queretaro Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Israel","family":"Ju\u00e1rez\u2010Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Fetal Medicine and Surgery Center Medicina Fetal M\u00e9xico, and Fetal Medicine Mexico Foundation  Queretaro Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo","family":"L\u00f3pez\u2010Briones","sequence":"additional","affiliation":[{"name":"Fetal Medicine and Surgery Center Medicina Fetal M\u00e9xico, and Fetal Medicine Mexico Foundation  Queretaro Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fausto","family":"Coronel\u2010Cruz","sequence":"additional","affiliation":[{"name":"Department of Maternal\u2010Fetal Medicine Hospital General de M\u00e9xico  Mexico City 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