{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T02:58:17Z","timestamp":1783133897523,"version":"3.54.6"},"reference-count":36,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,7,28]],"date-time":"2021-07-28T00:00:00Z","timestamp":1627430400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To examine the association between prenatal stomach position (SP) grade and stomach volume (SV) and the need for pulmonary hypertension (PH) treatment after birth in prenatally diagnosed left\u2010sided congenital diaphragmatic hernia (CDH), live born &gt;34 weeks.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In retrospect, SP grade and SV were determined in fetuses with isolated left\u2010sided CDH from 19 weeks gestational age (GA) onwards at three different time periods (\u226424 weeks' GA: US1, 24\u201330 weeks' GA: US2; \u226530 weeks' GA: US3). Primary outcome was need for treatment of PH after birth. Secondary analyses included the predictive value of SP and SV for other respiratory outcomes and postnatal defect size.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 101 fetuses were included. SP grade was significantly associated with need for treatment of PH (US1, US2, and US3: <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.02). Also, prenatal SP grade was positively associated with defect size and development of chronic lung disease (CLD) in survivors. No association was found between SV and respiratory morbidities or postnatal defect size.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>SP grade in left\u2010sided CDH fetuses is associated with an increased need for PH treatment, a larger postnatal defect size and CLD in survivors. We consider SP determination a valuable contribution to the prenatal assessment of left\u2010sided CDH.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.6019","type":"journal-article","created":{"date-parts":[[2021,7,22]],"date-time":"2021-07-22T14:56:18Z","timestamp":1626965778000},"page":"338-347","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Prenatal stomach position and volume in relation to postnatal outcomes in left\u2010sided congenital diaphragmatic hernia"],"prefix":"10.1002","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2808-5993","authenticated-orcid":false,"given":"Katinka","family":"Weller","sequence":"first","affiliation":[{"name":"Division of Obstetrics and Fetal Medicine Department of Obstetrics and Gynecology Erasmus MC\u2010Sophia Children's Hospital University Medical Center Rotterdam  Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2427-7269","authenticated-orcid":false,"given":"Nina C. 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