{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T03:10:26Z","timestamp":1771211426411,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2021,10,5]],"date-time":"2021-10-05T00:00:00Z","timestamp":1633392000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Right ventricular outflow tract abnormalities (RVOTA) have been mostly reported in recipient twins (RT) of monochorionic\/diamniotic (MC\/DA) twin pregnancies with twin\u2010to\u2010twin transfusion syndrome (TTTS). Aim of the study was to describe RVOTA detected in MC\/DA pregnancies without TTTS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Cases of RVOTA were retrieved from our database among all MC\/DA pregnancies without TTTS from 2009 to 2018.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Out of 891\u00a0MC\/DA twin pregnancies without TTTS, 14 (1.6%) were associated with RVOTA: 10 pulmonary stenosis (PS), one steno\u2010insufficiency, one insufficiency and two atresia (PA). In 93% of cases (13\/14), pregnancy was complicated either by amniotic fluid discrepancy (AFD) or by TAPS or mostly by selective fetal growth restriction (sFGR) (11\/13: 85%), involving predominantly (10\/11: 91%) the large twin, with high incidence (9\/11: 82%) of sFGR and AFD coexistence. Eight out of 14 (57%) survived after the perinatal period (7 PS, 1 PA). Five (62%) underwent pulmonary balloon valvuloplasty, whereas 3 children still showed persistent mild PS at cardiac follow up after 1\u00a0year of life.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>RVOTA can occur in MC\/DA pregnancies without TTTS, particularly when other complications coexist. In complicated cases specialized fetal echocardiographic evaluation is recommended during pregnancy; RVOTA cases should be delivered in a tertiary level center, where cardiologists are available.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.6052","type":"journal-article","created":{"date-parts":[[2021,9,29]],"date-time":"2021-09-29T04:14:51Z","timestamp":1632888891000},"page":"1510-1517","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Right ventricular outflow tract abnormalities in monochorionic twin pregnancies without twin\u2010to\u2010twin transfusion syndrome: Prenatal course and postnatal long\u2010term outcomes"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5537-7145","authenticated-orcid":false,"given":"Stefano","family":"Faiola","sequence":"first","affiliation":[{"name":"Fetal Therapy Unit\u2014Umberto Nicolini Vittore Buzzi Children's Hospital  Milan 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