{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T18:21:31Z","timestamp":1767982891082,"version":"3.49.0"},"reference-count":7,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,4,28]],"date-time":"2022-04-28T00:00:00Z","timestamp":1651104000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Key points<\/jats:title><jats:p><jats:bold>What's already known?<\/jats:bold>\n<jats:list list-type=\"bullet\">\n<jats:list-item>\n<jats:p>Variants in CCND2 gene are known to cause syndromic macrocephaly. Recently inverse growth proximal variants were described in five individuals with microcephaly.<\/jats:p><\/jats:list-item>\n<\/jats:list>\n<\/jats:p><jats:p><jats:bold>What does this study add?<\/jats:bold>\n<jats:list list-type=\"bullet\">\n<jats:list-item>\n<jats:p>CCND2 loss of function distal variants can cause fetal microcephaly.<\/jats:p><\/jats:list-item>\n<\/jats:list>\n<\/jats:p>","DOI":"10.1002\/pd.6148","type":"journal-article","created":{"date-parts":[[2022,4,19]],"date-time":"2022-04-19T06:18:37Z","timestamp":1650349117000},"page":"1343-1345","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Prenatal diagnosis of microcephaly as shown by plateauing of head circumference growth during the 3rd trimester in a\u00a0fetus with a CCND2 inverse growth variant"],"prefix":"10.1002","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0864-206X","authenticated-orcid":false,"given":"Gustavo","family":"Malinger","sequence":"first","affiliation":[{"name":"Division of Ultrasound in Obstetrics &amp; 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