{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T01:03:53Z","timestamp":1790643833923,"version":"4.1.0"},"reference-count":23,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2022,5,4]],"date-time":"2022-05-04T00:00:00Z","timestamp":1651622400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100009592","name":"Beijing Municipal Science and Technology Commission","doi-asserted-by":"publisher","award":["Z201100005520074"],"award-info":[{"award-number":["Z201100005520074"]}],"id":[{"id":"10.13039\/501100009592","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Prenatal Diagnosis"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare the outcomes of monochorionic triamniotic (MCTA) triplets managed expectantly with those reduced to twins.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>This was a retrospective cohort study comparing expectant management (EM) with fetal reduction (FR) to twins in 43 consecutive MCTA triplets with 3 live fetuses at 11\u201314\u00a0weeks between 2012 and 2021.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Nineteen patients managed expectantly and 24 triplets reduced to twins were included. The rate of pregnancy with at least one survivor was 84.2% in the EM group and 66.7% in the FR group (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.190). Compared to the EM cases, triplets reduced to twins had a higher median gestational age at delivery (36.0 vs. 33.3\u00a0weeks; <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001), a higher mean birth weight (2244.3\u00a0\u00b1\u00a0488.6\u00a0g vs. 1751.1\u00a0\u00b1\u00a0383.2\u00a0g; <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001) and a lower risk of preterm birth before 34\u00a0weeks (11.8% vs. 64.7%; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.001). There were no significant differences in the risk of miscarriage, pregnancy complications and composite adverse neonatal outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In MCTA triplets, FR to twins could reduce the risk of preterm birth, whereas EM seems to be a reasonable choice when the priority is at least one survivor. However, due to the small sample size of this study, these findings must be interpreted with great caution.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pd.6161","type":"journal-article","created":{"date-parts":[[2022,4,29]],"date-time":"2022-04-29T06:49:13Z","timestamp":1651214953000},"page":"970-977","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Outcome of monochorionic triamniotic triplet pregnancies: Expectant management versus fetal reduction"],"prefix":"10.1002","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3731-9536","authenticated-orcid":false,"given":"Xinlu","family":"Meng","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Peking University Third Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Peking University 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